Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9745549 | 0.81 | MAPT (0.67) | ALDH1A1HSD17B10SMN1; SMN2TP53TSHR | |
| SCHEMBL9745568 | 0.81 | MAPT (0.67) | ALDH1A1HSD17B10SMN1; SMN2TP53TSHR | |
| SCHEMBL871606 | 0.70 | TAS2R38 (0.50) | PTPN1ALDH1A1HSD17B10EPHX1SMN1; SMN2 | |
| SCHEMBL27590292 | 0.70 | TP53 (0.56) | PTPN1HSD17B10EPHX1SMN1; SMN2TP53 | |
| Phosphoric Acid SCHEMBL28089172 | 0.70 | TP53 (0.50) | PTPN1ALDH1A1HSD17B10EPHX1SMN1; SMN2 | |
| SCHEMBL28258463 | 0.69 | TAS2R38 (0.50) | PTPN1ALDH1A1HSD17B10EPHX1SMN1; SMN2 | |
| SCHEMBL11184467 | 0.69 | TAS2R38 (0.50) | PTPN1ALDH1A1HSD17B10EPHX1SMN1; SMN2 | |
| SCHEMBL16139552 | 0.68 | EPHX2 (0.54) | PTPN1ALDH1A1HSD17B10EPHX1SMN1; SMN2 | |
| SCHEMBL14334383 | 0.68 | TP53 (0.48) | PTPN1ALDH1A1HSD17B10EPHX1SMN1; SMN2 | |
| N-Phenylbenzamide SCHEMBL1955809 | 0.68 | SIRT1 (0.74) | PTPN1SMN1; SMN2HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019032472-A1 | HIGH AFFINITY ENGINEERED MATRIPTASE INHIBITOR | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-02-14 | — | — | WO | disclosed |