Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20255053 | 0.91 | LTA4H (0.51) | MAPTALDH1A1HPGDLTA4HTSHR | |
| SCHEMBL25181350 | 0.87 | KLK5 (0.50) | LTA4HACEHDAC8PPARGPPARA | |
| SCHEMBL23834107 | 0.87 | KLK5 (0.50) | LTA4HACEHDAC8PPARGPPARA | |
| SCHEMBL31407356 | 0.86 | ACE (0.56) | ALDH1A1LTA4HTSHRGAAACE | |
| SCHEMBL20253488 | 0.81 | LTA4H (0.55) | HPGDLTA4HRAB9AHDAC8MAPK1 | |
| SCHEMBL20253474 | 0.81 | LTA4H (0.59) | LTA4HACEHDAC8PPARGPPARA | |
| SCHEMBL13325459 | 0.80 | LTA4H (0.47) | MAPTALDH1A1LTA4HACECYP1A2 | |
| SCHEMBL28286842 | 0.80 | ALDH1A1 (0.58) | MAPTALDH1A1HPGDGAAACE | |
| SCHEMBL28286840 | 0.80 | ALDH1A1 (0.58) | MAPTALDH1A1HPGDGAAACE | |
| SCHEMBL20253475 | 0.80 | LTA4H (0.58) | LTA4HACEHDAC8PPARACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10202334-B2 | Pendant amines and derivatives as inhibitors of leukotriene A4 hydrolase | CELTAXSYS, INC. (US) | 2019-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10202334-B2 | Pendant amines and derivatives as inhibitors of leukotriene A4 hydrolase | LTA4H, LTB4R, LTC4S | MAPT 2828/4885ALDH1A1 511/4885HPGD 322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.