Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 9/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 9/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 9/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | WDR91 | A4D1P6 | 3/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 8/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 8/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 8/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 8/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20726517 | 0.94 | PRKAG1 (0.39) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL20726432 | 0.90 | CDK1 (0.36) | PRKAG1PRKAA1PRKAB1ARSYK | |
| SCHEMBL20726500 | 0.90 | CDK1 (0.36) | PRKAG1PRKAA1PRKAB1ARSYK | |
| SCHEMBL20726527 | 0.89 | USP2 (0.41) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL20726510 | 0.85 | AR (0.41) | PRKAG1PRKAA1PRKAB1ARWDR91 | |
| SCHEMBL20726455 | 0.85 | PRKAB2 (0.35) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL20726352 | 0.84 | PRKAG1 (0.40) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL16824289 | 0.84 | PRKAG1 (0.36) | PRKAG1PRKAA1PRKAB1ARWDR91 | |
| SCHEMBL30629830 | 0.84 | PRKAG1 (0.36) | PRKAG1PRKAA1PRKAB1ARWDR91 | |
| SCHEMBL26114838 | 0.84 | PRKAG1 (0.36) | PRKAG1PRKAA1PRKAB1ARWDR91 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083611-B1 | OXINDOLE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE IN THE TREATMENT OF AMPK-RELATED DISEASES | SANOFI SA (FR) | 2019-02-13 | — | — | EP | disclosed |