Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16672418 | 0.88 | CLK1 (0.43) | LMNACLK1HTTALDH1A1DUSP3 | |
| SCHEMBL16672420 | 0.84 | CREBBP (0.52) | LMNACLK1HTTALDH1A1DUSP3 | |
| SCHEMBL20726653 | 0.83 | PTGS2 (0.53) | ALDH1A1BRD4MEN1MAPTKMT2A | |
| SCHEMBL20726643 | 0.79 | GAA (0.49) | HTTALDH1A1BRD4MEN1MAPT | |
| SCHEMBL16672368 | 0.74 | BRD4 (0.41) | LMNAHTTALDH1A1TP53BRD4 | |
| SCHEMBL20726657 | 0.71 | HDAC3 (0.38) | LMNAALDH1A1BRD4MAPTSMN1; SMN2 | |
| SCHEMBL15597595 | 0.71 | GAA (0.54) | CLK1HTTALDH1A1PDK1PDK2 | |
| SCHEMBL16672371 | 0.71 | GFER (0.46) | LMNACLK1ALDH1A1MEN1MAPT | |
| SCHEMBL28378797 | 0.71 | MAPT (0.57) | LMNACLK1HTTALDH1A1PDK1 | |
| SCHEMBL16672372 | 0.71 | MAPT (0.45) | CLK1TP53MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060549-B1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | DAE WOONG PHARMA (KR) | 2019-02-13 | — | — | EP | disclosed |