Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 6/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20726653 | 0.85 | PTGS2 (0.53) | GAAMAPTALDH1A1BRD4RAB9A | |
| SCHEMBL20726641 | 0.79 | LMNA (0.45) | MAPTALDH1A1BRD4NPC1RAB9A | |
| SCHEMBL20726657 | 0.78 | HDAC3 (0.38) | GAAMAPTALDH1A1BRD4BRD9 | |
| SCHEMBL20726622 | 0.74 | MAP2K1 (0.46) | GAAMAPTGFERBRD4BRD9 | |
| SCHEMBL16672341 | 0.73 | PTGS2 (0.56) | GAAMAPTAGTR1ALDH1A1MAOB | |
| SCHEMBL16672381 | 0.72 | GAA (0.44) | GAAMAPTAGTR1ALDH1A1GFER | |
| SCHEMBL16672399 | 0.71 | GAA (0.48) | GAAMAPTAGTR1ALDH1A1GFER | |
| SCHEMBL16672371 | 0.70 | GFER (0.46) | GAAMAPTALDH1A1GFERMAOB | |
| SCHEMBL16672372 | 0.69 | MAPT (0.45) | GAAMAPTNPC1RAB9AKMT2A | |
| SCHEMBL480606 | 0.69 | BRD4 (0.50) | BRD4BRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060549-B1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | DAE WOONG PHARMA (KR) | 2019-02-13 | — | — | EP | disclosed |