Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 11/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16672358 | 0.80 | GAA (0.37) | BRD4GAAMAPTPOLBSMN1; SMN2 | |
| SCHEMBL20726653 | 0.79 | PTGS2 (0.53) | BRD4GAAMAPTSMN1; SMN2PTGS2 | |
| SCHEMBL20726622 | 0.79 | MAP2K1 (0.46) | HDAC3HDAC1HDAC2HDAC6BRD4 | |
| SCHEMBL20726643 | 0.78 | GAA (0.49) | BRD4BRD9GAAMAPTPOLB | |
| SCHEMBL16672412 | 0.74 | CREBBP (0.49) | HDAC3HDAC1HDAC2HDAC6GAA | |
| SCHEMBL16672372 | 0.72 | MAPT (0.45) | GAAMAPTPOLBSMN1; SMN2PTGS2 | |
| SCHEMBL20726641 | 0.71 | LMNA (0.45) | BRD4MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16672399 | 0.71 | GAA (0.48) | HDAC3HDAC1HDAC2HDAC6BRD4 | |
| SCHEMBL20726674 | 0.68 | CREBBP (0.45) | HDAC3HDAC1HDAC2HDAC6GAA | |
| SCHEMBL20726634 | 0.67 | GAA (0.56) | GAAMAPTPOLBSMN1; SMN2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060549-B1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | DAE WOONG PHARMA (KR) | 2019-02-13 | — | — | EP | disclosed |