Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.53 |
| ▸ | BRD4 | O60885 | 14/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20726643 | 0.85 | GAA (0.49) | PTGS2BRD4ALDH1A1GAAMAPT | |
| SCHEMBL20726641 | 0.83 | LMNA (0.45) | BRD4ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL20726657 | 0.79 | HDAC3 (0.38) | PTGS2BRD4ALDH1A1GAAMAPT | |
| SCHEMBL20726622 | 0.76 | MAP2K1 (0.46) | BRD4GAAMAPTMEN1KMT2A | |
| SCHEMBL26581408 | 0.75 | ALDH1A1 (0.50) | PTGS2BRD4ALDH1A1GAAMAPT | |
| SCHEMBL16672341 | 0.74 | PTGS2 (0.56) | PTGS2ALDH1A1GAAMAPTALOX12 | |
| SCHEMBL16672371 | 0.74 | GFER (0.46) | PTGS2ALDH1A1GAAMAPTHPGD | |
| SCHEMBL480606 | 0.73 | BRD4 (0.50) | BRD4 | |
| SCHEMBL16672372 | 0.73 | MAPT (0.45) | PTGS2GAAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL16672399 | 0.72 | GAA (0.48) | PTGS2BRD4ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060549-B1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | DAE WOONG PHARMA (KR) | 2019-02-13 | — | — | EP | disclosed |