Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21685864 | 0.83 | SIRT5 (0.38) | KMT2AMEN1GRM2HPGDTSHR | |
| SCHEMBL21685866 | 0.83 | SIRT5 (0.38) | KMT2AMEN1GRM2HPGDTSHR | |
| SCHEMBL20722557 | 0.83 | SIRT5 (0.38) | KMT2AMEN1GRM2HPGDTSHR | |
| SCHEMBL13484174 | 0.76 | HPGD (0.47) | KMT2AMEN1GRM2HPGDTSHR | |
| SCHEMBL28657596 | 0.74 | HDAC1 (0.44) | KMT2A | |
| SCHEMBL18740361 | 0.74 | HDAC1 (0.44) | KMT2A | |
| SCHEMBL21704252 | 0.74 | HDAC1 (0.44) | KMT2A | |
| SCHEMBL26119781 | 0.73 | FAAH (0.44) | HPGDTSHR | |
| SCHEMBL5745374 | 0.72 | PTPN1 (0.45) | KMT2AMEN1 | |
| SCHEMBL9846453 | 0.72 | PTPN1 (0.45) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019032863-A1 | CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2019-02-14 | — | — | WO | disclosed |