Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28980625 | 1.00 | ALDH1A1 (0.65) | ALDH1A1MAPTNPSR1HTTLMNA | |
| SCHEMBL9845673 | 1.00 | ALDH1A1 (0.65) | ALDH1A1MAPTNPSR1HTTLMNA | |
| SCHEMBL19195144 | 0.84 | ALDH1A1 (0.68) | ALDH1A1MAPTNPSR1HTTLMNA | |
| SCHEMBL17652439 | 0.84 | ALDH1A1 (0.68) | ALDH1A1MAPTNPSR1HTTLMNA | |
| SCHEMBL17652438 | 0.84 | ALDH1A1 (0.68) | ALDH1A1MAPTNPSR1HTTLMNA | |
| SCHEMBL19201600 | 0.83 | ALDH1A1 (0.66) | ALDH1A1MAPTNPSR1HTTLMNA | |
| SCHEMBL22683206 | 0.83 | ALDH1A1 (0.66) | ALDH1A1MAPTNPSR1HTTLMNA | |
| SCHEMBL19201601 | 0.83 | LMNA (0.66) | ALDH1A1MAPTNPSR1HTTLMNA | |
| SCHEMBL19209521 | 0.81 | MAPT (0.66) | ALDH1A1MAPTNPSR1HTTLMNA | |
| SCHEMBL9542426 | 0.81 | MAPT (0.66) | ALDH1A1MAPTNPSR1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685711-B2 | Carbon monoxide-releasing molecules triggered by physiological stimuli | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2023-06-27 | — | — | US | disclosed |
| US-11685711-B2 | Carbon monoxide-releasing molecules triggered by physiological stimuli | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2023-06-27 | — | — | US | disclosed |
| US-20200283382-A1 | CARBON MONOXIDE-RELEASING MOLECULES TRIGGERED BY PHYSIOLOGICAL STIMULI | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2020-09-10 | — | — | US | disclosed |
| WO-2019032879-A1 | CARBON MONOXIDE-RELEASING MOLECULES TRIGGERED BY PHYSIOLOGICAL STIMULI | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2019-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200283382-A1 | CARBON MONOXIDE-RELEASING MOLECULES TRIGGERED BY PHYSIOLOGICAL STIMULI | MB, CA2, HMOX2 | ALDH1A1 3046/4885MAPT 4592/4885NPSR1 384/4885 |
| US-11685711-B2 | Carbon monoxide-releasing molecules triggered by physiological stimuli | MB, CA2, HMOX2 | ALDH1A1 3046/4885MAPT 4592/4885NPSR1 384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.