Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13071505 | 0.84 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL11205335 | 0.80 | KMT2A (0.59) | NPC1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL11117595 | 0.79 | PTGS1 (0.47) | NPC1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL13588690 | 0.78 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL334252 | 0.78 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL9307123 | 0.77 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL8684173 | 0.76 | PPARA (0.45) | NPC1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL18612365 | 0.76 | AURKB (0.48) | NPC1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL18554124 | 0.76 | SMN1; SMN2 (0.44) | NPC1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL8686061 | 0.76 | PPARA (0.45) | NPC1RAB9ASMN1; SMN2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10702507-B2 | Endoparasite control agent | THE UNIVERSITY OF TOKYO (JP) | 2020-07-07 | — | — | US | disclosed |
| US-20190046511-A1 | ENDOPARASITE CONTROL AGENT | THE UNIVERSITY OF TOKYO (JP) | 2019-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190046511-A1 | ENDOPARASITE CONTROL AGENT | NAAA, CTRL, ENPP1 | NPC1 2985/4885RAB9A 722/4885SMN1; SMN2 4395/4885 |
| US-10702507-B2 | Endoparasite control agent | NAAA, CTRL, ENPP1 | NPC1 2985/4885RAB9A 722/4885SMN1; SMN2 4395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.