Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20734910 | 0.88 | MMP1 (0.48) | MAOBABCB1NPC1RAB9AMMP1 | |
| SCHEMBL20734898 | 0.84 | TSHR (0.45) | ABCB1IDO1MMP1MMP3MMP9 | |
| SCHEMBL20734899 | 0.84 | TSHR (0.45) | ABCB1IDO1MMP1MMP3MMP9 | |
| SCHEMBL20734912 | 0.83 | ALOX5 (0.42) | MAOBMRGPRX4RAB9AMAOA | |
| SCHEMBL20734901 | 0.83 | P2RX7 (0.46) | MAOBIDO1AGXTMAOA | |
| SCHEMBL20734907 | 0.83 | ALOX5 (0.42) | MAOBMRGPRX4RAB9AMAOA | |
| SCHEMBL20734900 | 0.83 | P2RX7 (0.46) | MAOBIDO1AGXTMAOA | |
| SCHEMBL20734807 | 0.80 | ALDH1A1 (0.44) | NPC1RAB9A | |
| SCHEMBL20734808 | 0.80 | ALDH1A1 (0.44) | NPC1RAB9A | |
| SCHEMBL20734921 | 0.79 | HRH3 (0.47) | MMP1MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3643311-A1 | 4-OXO-ALKYLATED TETRAMIC ACID COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Beijing Joekai Biotech. LLC (CN) | 2020-04-29 | — | — | EP | disclosed |