Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8370428 | 0.90 | HSD17B10 (0.50) | HPRT1HSD17B10ALDH1A1HPGDCYP1A2 | |
| SCHEMBL18600599 | 0.86 | HSD17B10 (0.50) | HPRT1HSD17B10ALDH1A1HPGDCYP1A2 | |
| SCHEMBL29407390 | 0.85 | HPRT1 (0.64) | HPRT1HSD17B10ALDH1A1HPGDCYP1A2 | |
| SCHEMBL175362 | 0.85 | HPRT1 (0.64) | HPRT1HSD17B10ALDH1A1HPGDCYP1A2 | |
| SCHEMBL869941 | 0.85 | HPRT1 (0.64) | HPRT1HSD17B10ALDH1A1HPGDCYP1A2 | |
| SCHEMBL20735859 | 0.85 | ALDH1A1 (0.59) | HPRT1HSD17B10ALDH1A1HPGDCYP1A2 | |
| SCHEMBL14743031 | 0.83 | HPRT1 (0.51) | HPRT1HSD17B10ALDH1A1HPGDCYP1A2 | |
| SCHEMBL6067770 | 0.83 | HPRT1 (0.37) | HPRT1HSD17B10ALDH1A1HPGDCYP1A2 | |
| SCHEMBL31668850 | 0.83 | KEAP1 (0.43) | HPRT1HSD17B10ALDH1A1HPGDCYP1A2 | |
| SCHEMBL992207 | 0.83 | KEAP1 (0.43) | HPRT1HSD17B10ALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10995217-B2 | Compounds as potential dye molecules | Lleaf Pty Ltd (AU) | 2021-05-04 | — | — | US | disclosed |
| US-20200199367-A1 | COMPOUNDS AS POTENTIAL DYE MOLECULES | Lleaf Pty Ltd (AU) | 2020-06-25 | — | — | US | disclosed |
| WO-2019028508-A1 | \"COMPOUNDS AS POTENTIAL DYE MOLECULES\ | Lleaf Pty Ltd (AU) | 2019-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200199367-A1 | COMPOUNDS AS POTENTIAL DYE MOLECULES | ALDH1A2, SDHA, TYR | HPRT1 912/4885HSD17B10 1347/4885ALDH1A1 5/4885 |
| US-10995217-B2 | Compounds as potential dye molecules | ALDH1A2, SDHA, TYR | HPRT1 912/4885HSD17B10 1347/4885ALDH1A1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.