Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70429 | 0.85 | LMNA (0.59) | KDM4EATMKMT2ALMNATSHR | |
| SCHEMBL254882 | 0.83 | TSHR (0.59) | KDM4EATMGAAKMT2ALMNA | |
| Hydrogen Peroxide SCHEMBL28473316 | 0.82 | TSHR (0.57) | KDM4EATMGAAKMT2ALMNA | |
| SCHEMBL647215 | 0.81 | CA1 (0.55) | KDM4EATMGAAKMT2ALMNA | |
| SCHEMBL7791811 | 0.81 | KDM4E (0.50) | KDM4EATMGAAKMT2ALMNA | |
| SCHEMBL18763821 | 0.81 | KDM4E (0.50) | KDM4EATMGAAKMT2ALMNA | |
| SCHEMBL23809124 | 0.80 | ACE2 (0.56) | KDM4EKMT2ALMNATSHRALDH1A1 | |
| SCHEMBL29197395 | 0.80 | LMNA (0.50) | KDM4EATMKMT2ALMNATSHR | |
| SCHEMBL3530454 | 0.79 | KDM4E (0.49) | KDM4EATMGAAKMT2ALMNA | |
| SCHEMBL16599453 | 0.79 | ALDH1A1 (0.53) | KDM4EATMGAAKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10807968-B2 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-10-20 | — | — | US | disclosed |
| US-20200048221-A1 | SUBSTITUTED 2-(HET)ARYLIMIDAZOLYLCARBOXYAMIDES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-13 | — | — | US | disclosed |
| US-10544124-B2 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-01-28 | — | — | US | disclosed |
| US-20190047982-A1 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190047982-A1 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | DDT, CYP4X1, CYP4Z1 | KDM4E 231/4885ATM 4555/4885GAA 1460/4885 |
| US-20200048221-A1 | SUBSTITUTED 2-(HET)ARYLIMIDAZOLYLCARBOXYAMIDES AS PESTICIDES | DDT, CYP4X1, CYP4Z1 | KDM4E 231/4885ATM 4555/4885GAA 1460/4885 |
| US-10807968-B2 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | DDT, CYP4X1, CYP4Z1 | KDM4E 231/4885ATM 4555/4885GAA 1460/4885 |
| US-10544124-B2 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | DDT, CYP4X1, CYP4Z1 | KDM4E 231/4885ATM 4555/4885GAA 1460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.