Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23384529 | 0.86 | HSD11B1 (0.45) | S1PR1POLBGABRDGABRA1GABRB1 | |
| SCHEMBL23384398 | 0.83 | ITGB3 (0.46) | S1PR1POLBGABRDGABRA1GABRB1 | |
| SCHEMBL20739480 | 0.78 | S1PR1 (0.44) | S1PR1POLBGABRDGABRA1GABRB1 | |
| SCHEMBL23357637 | 0.76 | S1PR1 (0.77) | S1PR1 | |
| SCHEMBL23384623 | 0.76 | S1PR1 (0.77) | S1PR1 | |
| SCHEMBL23384545 | 0.76 | S1PR1 (0.42) | S1PR1POLBGABRDGABRA1GABRB1 | |
| SCHEMBL20739606 | 0.72 | HPGD (0.51) | POLBCA12CA1CA2CA7 | |
| SCHEMBL20722178 | 0.72 | HPGD (0.51) | POLBCA12CA1CA2CA7 | |
| SCHEMBL20722166 | 0.71 | S1PR1 (0.77) | S1PR1 | |
| SCHEMBL23384541 | 0.71 | S1PR1 (0.41) | S1PR1GABRDGABRA1GABRB1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019032631-A1 | OXIME ETHER COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-02-14 | — | — | WO | disclosed |