Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20739480 | 0.91 | S1PR1 (0.44) | HSD11B1POLBGABRDGABRA1GABRB1 | |
| SCHEMBL23384398 | 0.88 | ITGB3 (0.46) | POLBGABRDGABRA1GABRB1GABRA5 | |
| SCHEMBL20739605 | 0.86 | S1PR1 (0.46) | POLBGABRDGABRA1GABRB1GABRA5 | |
| SCHEMBL23384545 | 0.80 | S1PR1 (0.42) | POLBGABRDGABRA1GABRB1GABRA5 | |
| SCHEMBL20739693 | 0.78 | HPGD (0.41) | HSD11B1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL20722196 | 0.77 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20722178 | 0.77 | HPGD (0.51) | POLBHPGDCA12CA1CA2 | |
| SCHEMBL20739606 | 0.77 | HPGD (0.51) | POLBHPGDCA12CA1CA2 | |
| SCHEMBL23384541 | 0.75 | S1PR1 (0.41) | GABRDGABRA1GABRB1GABRA5GABRA3 | |
| SCHEMBL11376680 | 0.75 | HPGD (0.76) | HSD11B1ALDH1A1HPGDCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11059784-B2 | Oxime ether compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-07-13 | — | — | US | disclosed |
| US-20210147361-A1 | OXIME ETHER COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147361-A1 | OXIME ETHER COMPOUNDS | S1PR1, S1PR3, S1PR2 | HSD11B1 859/4885POLB 2678/4885GABRD 3028/4885 |
| US-11059784-B2 | Oxime ether compounds | S1PR1, S1PR3, S1PR2 | HSD11B1 868/4885POLB 2719/4885GABRD 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.