SCHEMBL20739683

SCHEMBL20739683

COc1cc(N(C)C)cc(OC)c1C1N(C)C(c2ccccc2)=C(c2ccccc2)N1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.37
▸ PDGFRB P09619 1/20 0.36
▸ CYBB P04839 1/20 0.34
▸ NOX4 Q9NPH5 1/20 0.34
▸ MCHR1 Q99705 1/20 0.34
▸ HTR7 P34969 2/20 0.34
▸ NQO2 P16083 1/20 0.34
▸ WHR1 P49842 1/20 0.34
▸ MAPK1 P28482 3/20 0.33
▸ CYP1A2 P05177 3/20 0.33
▸ CYP3A4 P08684 3/20 0.33
▸ CYP2D6 P10635 3/20 0.33
▸ CYP2C9 P11712 3/20 0.33
▸ CYP2C19 P33261 3/20 0.33
▸ HSD17B10 Q99714 3/20 0.33
▸ USP2 O75604 2/20 0.33
▸ ALOX15 P16050 2/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ CYP1A1 P04798 1/20 0.33
▸ CYP2E1 P05181 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20739825 0.84 LMNA (0.54) LMNAPDGFRBCYBBNOX4NQO2
SCHEMBL20739761 0.79 CRHR1 (0.36) LMNAPDGFRBHTR7NQO2MAPK1
SCHEMBL21972257 0.76 LMNA (0.49) LMNAPDGFRBNQO2MAPK1HSD17B10
SCHEMBL21972266 0.76 LMNA (0.49) LMNAPDGFRBNQO2MAPK1HSD17B10
SCHEMBL20739824 0.75 LMNA (0.36) LMNAPDGFRBHTR7NQO2HSD17B10
SCHEMBL20739675 0.73 KDM4E (0.36) LMNACYBBNOX4HTR7NQO2
SCHEMBL21972265 0.73 LMNA (0.46) LMNAPDGFRBCYBBNOX4NQO2
SCHEMBL23097766 0.69 LMNA (0.33) LMNAPDGFRBNQO2
SCHEMBL21971404 0.69 LMNA (0.58) LMNAPDGFRBCYP1A2CYP3A4CYP2D6
SCHEMBL20739823 0.69 LMNA (0.50) LMNAPDGFRBCYBBNOX4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3416205-B1 LIGHT-EMITTING ELEMENT AND METHOD FOR MANUFACTURING SAME SUMITOMO CHEMICAL CO (JP) 2021-03-17 — — EP disclosed
US-10711091-B2 Light-emitting device and method for producing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-07-14 — — US disclosed
US-20190048131-A1 LIGHT-EMITTING DEVICE AND METHOD FOR PRODUCING SAME CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2019-02-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10711091-B2 Light-emitting device and method for producing same SCO2, SUN2, SLC18A2 LMNA 919/4885PDGFRB 4805/4885CYBB 777/4885
US-20190048131-A1 LIGHT-EMITTING DEVICE AND METHOD FOR PRODUCING SAME SCO2, SUN2, SLC18A2 LMNA 919/4885PDGFRB 4805/4885CYBB 777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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