Sulfuric Acid

Sulfuric Acid

SCHEMBL2073978

CCN1CCOCC1.O.O=S(=O)(O)O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.42
HSD17B10 Q99714 2/20 0.42
TSHR P16473 2/20 0.41
ALOX15 P16050 1/20 0.41
GAA P10253 1/20 0.41
ALDH1A1 P00352 2/20 0.40
USP2 O75604 1/20 0.40
GLA P06280 1/20 0.39
CA12 O43570 1/20 0.39
CA7 P43166 1/20 0.39
CA14 Q9ULX7 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL3384272 0.98 KDM4E (0.43) KDM4EHSD17B10TSHRALOX15GAA
Sulfuric Acid SCHEMBL11797700 0.98 KDM4E (0.43) KDM4EHSD17B10TSHRALOX15GAA
Water SCHEMBL7481158 0.86
Tetramethylammonium Ion SCHEMBL8829717 0.84 L3MBTL1 (0.42) KDM4EHSD17B10TSHRALOX15GAA
SCHEMBL474212 0.83
SCHEMBL3167 0.83
SCHEMBL8135220 0.83
Fluoride SCHEMBL7750159 0.83
Fluoride SCHEMBL11426086 0.83 USP2 (0.46) KDM4EHSD17B10TSHRALOX15GAA
SCHEMBL28231022 0.83 USP2 (0.46) KDM4EHSD17B10TSHRALOX15GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200131196-A1 Rapamycin Analog MOUNT TAM THERAPEUTICS, INC. (US) 2020-04-30 US disclosed
EP-3576736-A1 RAPAMYCIN ANALOG Mount Tam Therapeutics, Inc. (US) 2019-12-11 EP disclosed
WO-2018148508-A1 RAPAMYCIN ANALOG MOUNT TAM BIOTECHNOLOGIES, INC. (US) 2018-08-16 WO disclosed
EP-2797929-B1 NOVEL RAPAMYCIN ANALOGUE BUCK INST RES AGING (US) 2018-02-14 EP disclosed
US-9605001-B2 Production of polyketides and other natural products BUCK INSTITUTE FOR RESEARCH ON AGING (US) 2017-03-28 US disclosed
US-9382266-B2 Rapamycin analogue BUCK INSTITUTE FOR RESEARCH ON AGING (US) 2016-07-05 US disclosed
EP-2471797-B1 17-DESMETHYLRAPAMYCIN AND ANALOGUES THEREOF, METHODS FOR THEIR PRODUCTION AND THEIR USE AS IMMUNOSUPRESSANTS, ANTICANCER AGENTS, ANTIFUNGAL AGENTS ETC. BUCK INST FOR RES ON AGING (US) 2016-02-03 EP disclosed
US-20150266896-A1 PRODUCTION OF POLYKETIDES AND OTHER NATURAL PRODUCTS BIOTICA TECH LTD (GB) 2015-09-24 US disclosed
US-20150210714-A1 NOVEL RAPAMYCIN ANALOGUE BUCK INSTITUTE FOR RESEARCH ON AGING 2015-07-30 US disclosed
EP-1521828-B1 PRODUCTION OF POLYKETIDES BUCK INST FOR RES ON AGING (US) 2015-07-01 EP disclosed
WO-2006095185-A1 39-DESMETHOXY DERIVATIVES OF RAPAMYCIN BIOTICA TECHNOLOGY LIMITED (GB) 2006-09-14 WO disclosed
US-20060205757-A1 39-desmethoxyrapamycin, compositions and methods of use thereof BIOTICA TECHNOLOGY LIMITED (GB) 2006-09-14 US disclosed
EP-1655372-A2 Production of polyketides and other natural products Biotica Technology Limited (GB) 2006-05-10 EP disclosed
US-20060078980-A1 Production of polyketides and other natural products GREGORY MATTHEW A 2006-04-13 US disclosed
WO-2006016167-A2 17-DESMETHYLRAPAMYCIN AND ANALOGUES THEREOF, METHODS FOR THEIR RODUCTION AND THEIR USE AS IMMUNOSUPRESSANTS, ANTICANCER AGENTS, ANTIFUNGAL AGENTS, ETC. BIOTICA TECHNOLOGY LIMITED (GB) 2006-02-16 WO disclosed
US-20050272132-A1 Production of polyketides and other natural products BIOTICA TECHNOLOGY LIMITED (GB) 2005-12-08 US disclosed
EP-1589031-A2 Production of polyketides and other natural products Biotica Technology Limited (GB) 2005-10-26 EP disclosed
CN-1668741-A Production of polyketides and other natural products BIOTICA TECH LTD (GB) 2005-09-14 CN disclosed
EP-1521828-A2 PRODUCTION OF POLYKETIDES Biotica Technology Limited (GB) 2005-04-13 EP disclosed
WO-2004007709-A2 PRODUCTION OF POLYKETIDES BIOTICA TECHNOLOGY LIMITED (GB) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150266896-A1 PRODUCTION OF POLYKETIDES AND OTHER NATURAL PRODUCTS FKBP14, FKBP4, FKBP2 KDM4E 3459/4885HSD17B10 547/4885TSHR 3950/4885
US-20200131196-A1 Rapamycin Analog RICTOR, MTOR, RPTOR KDM4E 1838/4885HSD17B10 2503/4885TSHR 2662/4885
US-20150210714-A1 NOVEL RAPAMYCIN ANALOGUE MTOR, RICTOR, MAPKAP1 KDM4E 2862/4885HSD17B10 1388/4885TSHR 2898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.