Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.41 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21970632 | 0.82 | PDGFRB (0.42) | LMNAPDGFRBMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29414076 | 0.82 | LMNA (0.69) | LMNADRD2PDGFRBHTR2CMAPT | |
| SCHEMBL12978570 | 0.82 | LMNA (0.69) | LMNADRD2PDGFRBHTR2CMAPT | |
| SCHEMBL21972253 | 0.80 | PDGFRB (0.40) | LMNAPDGFRBHTR2CMAPTNPSR1 | |
| SCHEMBL21970999 | 0.76 | LMNA (0.56) | LMNADRD2PDGFRBMAPTNPSR1 | |
| SCHEMBL21971403 | 0.75 | LMNA (0.63) | LMNAPDGFRBNPC1MAPTSMN1; SMN2 | |
| SCHEMBL21971009 | 0.75 | LMNA (0.63) | LMNAPDGFRBNPC1MAPTSMN1; SMN2 | |
| SCHEMBL20739824 | 0.74 | LMNA (0.36) | LMNABRD4BRPF1PDGFRBSMN1; SMN2 | |
| SCHEMBL21970984 | 0.74 | PDGFRB (0.56) | LMNAPDGFRBMAPTALDH1A1 | |
| SCHEMBL21971000 | 0.73 | LMNA (0.49) | LMNABRD4BRPF1DRD2PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11046655-B2 | Compound and method for producing same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-06-29 | — | — | US | disclosed |
| US-20200140394-A1 | NOVEL COMPOUND AND METHOD FOR PRODUCING SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200140394-A1 | NOVEL COMPOUND AND METHOD FOR PRODUCING SAME | CBR3, NR2E3, NR5A2 | LMNA 4733/4885BRD4 1218/4885BRPF1 1165/4885 |
| US-11046655-B2 | Compound and method for producing same | CBR3, NR5A1, NR2E3 | LMNA 4570/4885BRD4 1654/4885BRPF1 1216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.