Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.39 |
| ▸ | CTSC | P53634 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11445364 | 0.80 | CTSS (0.43) | CTSCCTSS | |
| SCHEMBL2072810 | 0.79 | ALDH1A1 (0.36) | CTSCFFAR1FFAR4FAAHCTSS | |
| SCHEMBL7998696 | 0.77 | CTSS (0.42) | CTSCCTSS | |
| SCHEMBL7994665 | 0.77 | — | — | |
| SCHEMBL4410076 | 0.71 | GPR84 (0.33) | GPR84FFAR1FFAR4FAAH | |
| SCHEMBL2073589 | 0.70 | GPR84 (0.38) | GPR84FFAR1FFAR4FAAHACACB | |
| SCHEMBL23530055 | 0.70 | GPR84 (0.46) | GPR84FFAR1FFAR4ACACBACACA | |
| SCHEMBL30787207 | 0.70 | GPR84 (0.46) | GPR84FFAR1FFAR4ACACBACACA | |
| SCHEMBL30787116 | 0.70 | GPR84 (0.46) | GPR84FFAR1FFAR4ACACBACACA | |
| SCHEMBL30787291 | 0.70 | GPR84 (0.46) | GPR84FFAR1FFAR4ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863294-B2 | Heterocycle derivatives as histone deacetylase (HDAC) inhibitors | INSTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2011-01-04 | — | — | US | disclosed |