Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.42 |
| ▸ | CTSC | P53634 | 8/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11445364 | 0.86 | CTSS (0.43) | CTSSCTSCCTSKPOLBTAS1R3 | |
| SCHEMBL13311773 | 0.83 | CTSS (0.42) | CTSSCTSCCHRM1AKR1A1CHRM3 | |
| SCHEMBL7994665 | 0.83 | — | — | |
| SCHEMBL28132954 | 0.79 | CTSC (0.40) | CTSCCTSKCYP3A4CYP1A2CTSH | |
| SCHEMBL6429832 | 0.79 | CHRM1 (0.38) | CTSSCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL2074129 | 0.77 | GPR84 (0.39) | CTSSCTSC | |
| SCHEMBL2072810 | 0.76 | ALDH1A1 (0.36) | CTSSCTSCHDAC1HDAC2HDAC8 | |
| SCHEMBL28886656 | 0.75 | CHRM1 (0.39) | CTSSCTSCCHRM1AKR1A1CHRM3 | |
| SCHEMBL17091717 | 0.75 | CHRM1 (0.34) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL6654092 | 0.74 | CTSK (0.58) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284892-B1 | Method for producing salts of cyclic amidines | DEGUSSA HUELS AKTIENGESELLSCHAFT (DE) | 2001-09-04 | — | — | US | disclosed |