SCHEMBL20743116

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20743061	0.83	JAK2 (0.45)	JAK2JAK1SMN1; SMN2NPC1RAB9A
	SCHEMBL22059523	0.81	GRIN2B (0.54)	JAK2JAK1SMN1; SMN2NPC1RAB9A
	SCHEMBL30328633	0.74	RORC (0.38)	SMN1; SMN2NPC1RAB9AGRIN2BFAAH
	SCHEMBL20743055	0.74	MAP3K12 (0.44)	MEN1KMT2AUSP30MAP3K12
	SCHEMBL16158890	0.73	SMN1; SMN2 (0.58)	JAK2JAK1SMN1; SMN2NPC1RAB9A
	SCHEMBL19404912	0.73	GRIN2B (0.58)	JAK2JAK1SMN1; SMN2NPC1RAB9A
	SCHEMBL2621378	0.73	SMN1; SMN2 (0.61)	SMN1; SMN2NPC1RAB9AGRIN2BCYP2C19
	SCHEMBL70761	0.73	SMN1; SMN2 (0.61)	SMN1; SMN2NPC1RAB9AGRIN2BCYP2C19
	SCHEMBL2621382	0.73	SMN1; SMN2 (0.61)	SMN1; SMN2NPC1RAB9AGRIN2BCYP2C19
	SCHEMBL70762	0.73	SMN1; SMN2 (0.61)	SMN1; SMN2NPC1RAB9AGRIN2BCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.