Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 8/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6793430 | 0.92 | HPGDS (0.83) | HPGDSHPGDHTTALDH1A1NPC1 | |
| SCHEMBL8439895 | 0.84 | HPGDS (0.78) | HPGDSHPGDHTTALDH1A1NPC1 | |
| SCHEMBL158020 | 0.83 | HPGDS (1.00) | HPGDSHPGDHTTALDH1A1NPC1 | |
| SCHEMBL6326690 | 0.82 | HPGD (1.00) | HPGDSHPGDHTTALDH1A1NPC1 | |
| SCHEMBL5591866 | 0.82 | HPGDS (0.69) | HPGDSHPGDHTTALDH1A1NPC1 | |
| SCHEMBL2074541 | 0.82 | HPGDS (0.69) | HPGDSHPGDHTTALDH1A1NPC1 | |
| SCHEMBL4420563 | 0.82 | HPGDS (0.69) | HPGDSHPGDHTTALDH1A1NPC1 | |
| SCHEMBL11306574 | 0.82 | HPGDS (0.69) | HPGDSHPGDHTTALDH1A1NPC1 | |
| SCHEMBL2760408 | 0.82 | HPGDS (0.69) | HPGDSHPGDHTTALDH1A1NPC1 | |
| SCHEMBL7075260 | 0.82 | HPGDS (0.69) | HPGDSHPGDHTTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253879-A1 | TOPICAL ANTIINFLAMMATORY COMPOSITIONS | RIKER LABORATORIES, INC. (US) | 1988-01-27 | — | — | EP | claimed |
| WO-1987004345-A1 | TOPICAL ANTIINFLAMMATORY COMPOSITIONS | RIKER LABORATORIES, INC. (US) | 1987-07-30 | — | — | WO | claimed |
| EP-0860433-B1 | QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF GROWTH FACTOR RECEPTOR ORIGINATING IN PLATELET AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KIRIN BREWERY (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-6143764-A | ETHER DERIVATIVES OF QUINOLINE, ANTITUMOR AGENTS | KIRIN BEER KABUSHIKI KAISHA (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0860433-A1 | QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF GROWTH FACTOR RECEPTOR ORIGINATING IN PLATELET AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 1998-08-26 | — | — | EP | disclosed |
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |
| US-4916147-A | 3-[(4-Aroyl) phenoxy (or phenylthio)]-cyclopentanecarboxylic acid analogues and treatment of cerebral edema therewith | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |
| EP-0210772-A2 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-02-04 | — | — | EP | disclosed |
| EP-0006407-B1 | HYDANTOIN DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1984-05-16 | — | — | EP | disclosed |
| US-4281009-A | SEDATIVES, ANALGESICS, ANTIULCER AGENTS, A HYPNOTIC AND ANTIHYPERTENSIVE AGENTS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1981-07-28 | — | — | US | disclosed |
| US-4259509-A | ANTICHOLESTEROL, ANTILIPEMIC, DIURETIC | ALBERT ROLLAND S.A. (FR) | 1981-03-31 | — | — | US | disclosed |
| US-4235896-A | Benzyl-phenoxy acid esters and hyperlipaemia compositions containing the same | ORCHIMED S.A. (CH) | 1980-11-25 | — | — | US | disclosed |
| US-4212882-A | ANTIINFLAMMATORY INTERMEDIATES | RIKER LABORATORIES, INC. (US) | 1980-07-15 | — | — | US | disclosed |
| EP-0006407-A1 | Hydantoin derivatives, their preparation and pharmaceutical compositions containing them | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1980-01-09 | — | — | EP | disclosed |
| US-4179515-A | HYPOLIPEMIC, HYPOCHOLESTEROLEMIC, CHOLAGOGIC | ORCHIMED S. A. (CH) | 1979-12-18 | — | — | US | disclosed |
| US-4172082-A | ANTIINFLAMMATORY AGENTS | RIKER LABORATORIES, INC. (US) | 1979-10-23 | — | — | US | disclosed |