Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.83 |
| ▸ | HPGD | P15428 | 7/20 | 0.81 |
| ▸ | HTT | P42858 | 2/20 | 0.81 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | CES2 | O00748 | 1/20 | 0.62 |
| ▸ | CES1 | P23141 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | DAO | P14920 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7485708 | 0.92 | HPGDS (0.71) | HPGDSHPGDHTTNPC1RAB9A | |
| SCHEMBL8439895 | 0.92 | HPGDS (0.78) | HPGDSHPGDHTTNPC1RAB9A | |
| SCHEMBL158020 | 0.91 | HPGDS (1.00) | HPGDSHPGDHTTNPC1RAB9A | |
| SCHEMBL4420563 | 0.90 | HPGDS (0.69) | HPGDSHPGDHTTNPC1RAB9A | |
| SCHEMBL11306574 | 0.90 | HPGDS (0.69) | HPGDSHPGDHTTNPC1RAB9A | |
| SCHEMBL2760408 | 0.90 | HPGDS (0.69) | HPGDSHPGDHTTNPC1RAB9A | |
| SCHEMBL6326690 | 0.90 | HPGD (1.00) | HPGDSHPGDHTTNPC1RAB9A | |
| SCHEMBL5591866 | 0.90 | HPGDS (0.69) | HPGDSHPGDHTTNPC1RAB9A | |
| SCHEMBL2074541 | 0.90 | HPGDS (0.69) | HPGDSHPGDHTTNPC1RAB9A | |
| SCHEMBL7075260 | 0.90 | HPGDS (0.69) | HPGDSHPGDHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354836-A | Polyarylene ether ketone, where at least one ring of the aromatic ketone unit is a thiophene ring | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1994-10-11 | — | — | US | claimed |
| US-20040038076-A1 | Poly (paraphenylenevinylene) derivatives and their use as electroluminescence materials | KREUDER WILLI (DE) | 2004-02-26 | — | — | US | disclosed |
| EP-0783555-B1 | POLY(PARAPHENYLENE VINYLENE) DERIVATIVES AND THEIR USE AS ELECTROLUMINESCENT MATERIALS | COVION ORGANIC SEMICONDUCTORS (DE) | 2002-12-11 | — | — | EP | disclosed |
| US-20010031378-A1 | Poly (paraphenylenevinylene) derivatives and their use as electroluminescence materials | KREUDER WILLI (DE) | 2001-10-18 | — | — | US | disclosed |
| US-5420224-A | Films and fibers with benzoxazole groups | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1995-05-30 | — | — | US | disclosed |
| US-5354836-A | Polyarylene ether ketone, where at least one ring of the aromatic ketone unit is a thiophene ring | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1994-10-11 | — | — | US | disclosed |
| US-5266677-A | Aromatic polyamides | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1993-11-30 | — | — | US | disclosed |