Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | HPGDS | O60760 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6793430 | 0.90 | HPGDS (0.83) | HPGDHTTHPGDSMAPTMEN1 | |
| SCHEMBL7485708 | 0.82 | HPGDS (0.71) | HPGDHTTHPGDSMAPTMEN1 | |
| SCHEMBL8439895 | 0.82 | HPGDS (0.78) | HPGDHTTHPGDSMAPTMEN1 | |
| SCHEMBL158020 | 0.82 | HPGDS (1.00) | HPGDHTTHPGDSMAPTMEN1 | |
| SCHEMBL5591866 | 0.81 | HPGDS (0.69) | HPGDHTTHPGDSMAPTMEN1 | |
| SCHEMBL4420563 | 0.81 | HPGDS (0.69) | HPGDHTTHPGDSMAPTMEN1 | |
| SCHEMBL2760408 | 0.81 | HPGDS (0.69) | HPGDHTTHPGDSMAPTMEN1 | |
| SCHEMBL11306574 | 0.81 | HPGDS (0.69) | HPGDHTTHPGDSMAPTMEN1 | |
| SCHEMBL2074541 | 0.81 | HPGDS (0.69) | HPGDHTTHPGDSMAPTMEN1 | |
| SCHEMBL7075260 | 0.81 | HPGDS (0.69) | HPGDHTTHPGDSMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124664-A1 | Urea thiadiazole inhibitors of plasminogen activator inhibior-1 | BRISTOL-MYERS SQUIBB CO. | 2005-06-09 | — | — | US | disclosed |
| US-4980349-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTICOAGULANTS | SANOFI (FR) | 1990-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124664-A1 | Urea thiadiazole inhibitors of plasminogen activator inhibior-1 | SERPINE1, SERPINC1, SERPINB1 | HPGD 149/4885HTT 2797/4885HPGDS 775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.