SCHEMBL20746321

SCHEMBL20746321

CCOC(=O)c1cc2cc(/N=N/c3ccc(N(C)C)cc3)ccc2[nH]1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.60
KDM4E B2RXH2 3/20 0.60
ALDH1A1 P00352 3/20 0.60
HPGD P15428 3/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
HSD17B10 Q99714 1/20 0.60
NPC1 O15118 3/20 0.56
LMNA P02545 2/20 0.56
HTT P42858 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
HRH3 Q9Y5N1 1/20 0.56
MMP13 P45452 8/20 0.55
MMP2 P08253 6/20 0.55
MAPT P10636 2/20 0.52
MEN1 O00255 1/20 0.52
GLA P06280 1/20 0.52
GAA P10253 1/20 0.52
KMT2A Q03164 1/20 0.52
ATM Q13315 1/20 0.52
MMP14 P50281 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1474801 0.86 KDM4E (0.70) RAB9AKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL22049916 0.83 NPC1 (0.54) RAB9AKDM4EALDH1A1HSD17B10NPC1
SCHEMBL20764374 0.83 NPC1 (0.54) RAB9AKDM4EALDH1A1HPGDHSD17B10
SCHEMBL20764157 0.82 NPC1 (0.40) RAB9AKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL28057068 0.81 KDM4E (0.65) RAB9AKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL22718574 0.78 MMP13 (0.67) RAB9AKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL6517751 0.78 KDM4E (0.68) RAB9AKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL15904606 0.77 KDM4E (0.64) RAB9AKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL18821733 0.76 NPC1 (0.70) RAB9AKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL30994860 0.76 RAB9A (1.00) RAB9AKDM4EALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11320376-B2 Duplex stabilizing fluorescence quenchers for nucleic acid probes ELITECHGROUP MDX LLC (US) 2022-05-03 US disclosed
US-11320376-B2 Duplex stabilizing fluorescence quenchers for nucleic acid probes ELITECHGROUP MDX LLC (US) 2022-05-03 US disclosed
EP-3668884-B1 DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES ELITECHGROUP INC (US) 2022-03-09 EP disclosed
US-20210041360-A1 DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES ELITECHGROUP, INC. (US) 2021-02-11 US disclosed
US-20210041360-A1 DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES ELITECHGROUP, INC. (US) 2021-02-11 US disclosed
US-10890529-B2 Duplex stabilizing fluorescence quenchers for nucleic acid probes ELITECHGROUP, INC. (US) 2021-01-12 US disclosed
US-10890529-B2 Duplex stabilizing fluorescence quenchers for nucleic acid probes ELITECHGROUP, INC. (US) 2021-01-12 US disclosed
EP-3668884-A1 DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES ELITechGroup Inc. (US) 2020-06-24 EP disclosed
US-10677728-B2 Duplex stabilizing fluorescence quenchers for nucleic acid probes ELITECHGROUP B.V. (NL) 2020-06-09 US disclosed
US-10677728-B2 Duplex stabilizing fluorescence quenchers for nucleic acid probes ELITECHGROUP B.V. (NL) 2020-06-09 US disclosed
US-20200173924-A1 DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES ELITECHGROUP, INC. (US) 2020-06-04 US disclosed
US-20200173924-A1 DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES ELITECHGROUP, INC. (US) 2020-06-04 US disclosed
WO-2019036225-A1 DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES ELITECHGROUP, INC. (US) 2019-02-21 WO disclosed
WO-2019036225-A1 DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES ELITECHGROUP, INC. (US) 2019-02-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10677728-B2 Duplex stabilizing fluorescence quenchers for nucleic acid probes DDB1, DUT, DCLRE1B RAB9A 4274/4885KDM4E 3827/4885ALDH1A1 1848/4885
US-20200173924-A1 DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES DDB1, DUT, DCLRE1B RAB9A 4274/4885KDM4E 3827/4885ALDH1A1 1848/4885
US-10890529-B2 Duplex stabilizing fluorescence quenchers for nucleic acid probes DDB1, DUT, DCLRE1B RAB9A 4274/4885KDM4E 3827/4885ALDH1A1 1848/4885
US-11320376-B2 Duplex stabilizing fluorescence quenchers for nucleic acid probes DDB1, DUT, DCLRE1B RAB9A 4274/4885KDM4E 3827/4885ALDH1A1 1848/4885
US-20210041360-A1 DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES DDB1, DUT, DCLRE1B RAB9A 4274/4885KDM4E 3827/4885ALDH1A1 1848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.