Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CHIT1 | Q13231 | 2/20 | 0.33 |
| ▸ | CHIA | Q9BZP6 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | CHI3L1 | P36222 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | CTSE | P14091 | 1/20 | 0.33 |
| ▸ | PGC | P20142 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18609787 | 1.00 | TRPA1 (0.35) | TRPA1KCNH2CHIT1CHIAALDH1A1 | |
| SCHEMBL18589498 | 1.00 | TRPA1 (0.35) | TRPA1KCNH2CHIT1CHIAALDH1A1 | |
| SCHEMBL18577070 | 1.00 | TRPA1 (0.35) | TRPA1KCNH2CHIT1CHIAALDH1A1 | |
| SCHEMBL18607945 | 1.00 | TRPA1 (0.35) | TRPA1KCNH2CHIT1CHIAALDH1A1 | |
| Hydrochloric Acid SCHEMBL18577264 | 0.98 | REN (0.34) | TRPA1KCNH2CHIT1CHIAALDH1A1 | |
| Hydrochloric Acid SCHEMBL18577192 | 0.98 | REN (0.34) | TRPA1KCNH2CHIT1CHIAALDH1A1 | |
| SCHEMBL22901990 | 0.85 | POLB (0.37) | TRPA1KCNH2ALDH1A1LMNALTA4H | |
| SCHEMBL26210924 | 0.83 | LTA4H (0.40) | KCNH2LTA4H | |
| SCHEMBL26210919 | 0.83 | LTA4H (0.40) | KCNH2LTA4H | |
| Hydrochloric Acid SCHEMBL28686340 | 0.83 | POLB (0.36) | KCNH2ALDH1A1LMNALTA4HREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009209-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS CHITINASE INHIBITORS | Oncoarendi Therapeutics S.A. (PL) | 2021-01-21 | — | — | WO | disclosed |
| US-10208020-B2 | Substituted amino triazoles useful as human chitinase inhibitors | Oncoarendi Therapeutics S.A. (PL) | 2019-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10208020-B2 | Substituted amino triazoles useful as human chitinase inhibitors | CHIA, CHIT1, AADAC | TRPA1 588/4885KCNH2 3882/4885CHIT1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.