Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20747628 | 0.90 | LMNA (0.49) | LMNAHSD17B10GRIN2DGRIN3BGRIN1 | |
| SCHEMBL20747608 | 0.87 | LMNA (0.41) | LMNAHSD17B10GRIN2DGRIN3BGRIN1 | |
| SCHEMBL20747640 | 0.86 | GRIN2D (0.43) | LMNAHSD17B10GRIN2DGRIN3BGRIN1 | |
| SCHEMBL20747677 | 0.81 | GRIN2D (0.47) | LMNAHSD17B10GRIN2DGRIN3BGRIN1 | |
| SCHEMBL20747678 | 0.81 | GRIN2D (0.42) | LMNAHSD17B10GRIN2DGRIN3BGRIN1 | |
| SCHEMBL24943436 | 0.80 | NAAA (0.40) | TSHRRAB9AMAPTMEN1KMT2A | |
| SCHEMBL20747637 | 0.79 | GRIN2D (0.41) | LMNAHSD17B10GRIN2DGRIN3BGRIN1 | |
| SCHEMBL20747768 | 0.78 | GRIN2D (0.45) | LMNAHSD17B10GRIN2DGRIN3BGRIN1 | |
| SCHEMBL20224654 | 0.77 | ALDH1A1 (0.38) | LMNAHSD17B10GRIN2DGRIN3BGRIN1 | |
| SCHEMBL21246104 | 0.77 | LMNA (0.41) | LMNAHSD17B10CYP3A4TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10208045-B2 | Aza-pyridone compounds and uses thereof | ALIOS BIOPHARMA, INC. (US) | 2019-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10208045-B2 | Aza-pyridone compounds and uses thereof | PNPO, ITPA, PDXK | LMNA 2972/4885HSD17B10 3567/4885GRIN2D 4153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.