Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 9/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498127 | 0.84 | ALDH1A1 (0.62) | PDE4BFDPSPDE4APDE4CPDE4D | |
| SCHEMBL30352601 | 0.84 | ALDH1A1 (0.62) | PDE4BFDPSPDE4APDE4CPDE4D | |
| SCHEMBL637014 | 0.81 | FDPS (0.67) | PDE4BFDPSPDE4APDE4CPDE4D | |
| SCHEMBL13232716 | 0.81 | DRD2 (0.47) | PDE4BFDPSPDE4APDE4CPDE4D | |
| SCHEMBL3736992 | 0.81 | FDPS (0.43) | PDE4BFDPSPDE4APDE4CPDE4D | |
| SCHEMBL6584890 | 0.80 | ALDH1A1 (0.60) | PDE4BFDPSPDE4APDE4CPDE4D | |
| SCHEMBL18883604 | 0.80 | ALDH1A1 (0.57) | FDPSALDH1A1TSHRTACR2HPGD | |
| SCHEMBL29991604 | 0.80 | ALDH1A1 (0.57) | FDPSALDH1A1TSHRTACR2HPGD | |
| SCHEMBL17050362 | 0.80 | PDE4B (0.46) | PDE4BFDPSPDE4APDE4CPDE4D | |
| SCHEMBL5451545 | 0.80 | HPGD (0.54) | PDE4BFDPSPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928869-B1 | 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARM SPA (IT) | 2019-02-20 | — | — | EP | disclosed |