SCHEMBL4574419

SCHEMBL4574419

COC1CC1NC(=O)OCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CPB1 P15086 2/20 0.63
ALDH1A1 P00352 4/20 0.55
GAA P10253 1/20 0.55
TSHR P16473 2/20 0.52
CYP2C9 P11712 2/20 0.49
CYP2C19 P33261 2/20 0.49
CYP1A2 P05177 1/20 0.49
POLB P06746 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
EPHX1 P07099 1/20 0.49
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
ACHE P22303 2/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
CTSL P07711 1/20 0.47
CTSB P07858 1/20 0.47
CTSK P43235 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31470357 0.87 CPB1 (0.57) CPB1ALDH1A1GAATSHREPHX1
SCHEMBL19630135 0.86 CPB1 (0.58) CPB1ALDH1A1GAATSHREPHX1
SCHEMBL20749075 0.86 CPB1 (0.58) CPB1ALDH1A1GAATSHREPHX1
SCHEMBL28914414 0.86 CPB1 (0.58) CPB1ALDH1A1GAATSHREPHX1
SCHEMBL28914412 0.86 CPB1 (0.58) CPB1ALDH1A1GAATSHREPHX1
SCHEMBL24920352 0.86 ALDH1A1 (0.53) CPB1ALDH1A1GAATSHRCYP2C9
SCHEMBL2190928 0.85 CPB1 (0.55) CPB1ALDH1A1GAATSHRCYP2C9
SCHEMBL7501170 0.85 CPB1 (0.54) CPB1ALDH1A1GAATSHRCYP3A4
SCHEMBL29512123 0.84 KMT2A (0.53) CPB1ALDH1A1GAATSHREPHX1
SCHEMBL4574080 0.83 CPB1 (0.60) CPB1ALDH1A1GAATSHREPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008095912-A2 ENANTIOPURE PHARMACOLOGICALLY ACTIVE TRICYCLIC BENZIMIDAZOLES NYCOMED GMBH (DE) 2008-08-14 WO disclosed