Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19316154 | 0.81 | — | — | |
| SCHEMBL20749425 | 0.73 | ACHE (0.41) | ACHE | |
| Hydrochloric Acid SCHEMBL20740109 | 0.73 | MAOB (0.40) | SCN9AALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL19315988 | 0.71 | KDM4E (0.46) | ACHECYP2D6ALDH1A1KDM4ELMNA | |
| SCHEMBL25452836 | 0.70 | METAP1 (0.38) | AKR1B1ACHE | |
| SCHEMBL20672175 | 0.70 | METAP1 (0.38) | AKR1B1ACHEKDM4E | |
| SCHEMBL11837511 | 0.70 | NPY5R (0.45) | SCN9ACYP2D6KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL16694193 | 0.70 | SCN9A (0.35) | SCN9A | |
| SCHEMBL25171185 | 0.69 | BACE1 (0.41) | AKR1B1 | |
| SCHEMBL22898412 | 0.69 | NR1H2 (0.40) | ALDH1A1KDM4ELMNAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10399992-B2 | Process for preparing AD-35 | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2019-09-03 | — | — | US | disclosed |
| US-20190100527-A1 | Process For Preparing AD-35 | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2019-04-04 | — | — | US | disclosed |
| EP-3444253-A1 | PROCESS FOR PREPARING AD-35 | Zhejiang Hisun Pharmaceutical Co., Ltd. (CN) | 2019-02-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190100527-A1 | Process For Preparing AD-35 | NAA50, BBOX1, ADSL | AKR1B1 586/4885SCN9A 3546/4885ACHE 44/4885 |
| US-10399992-B2 | Process for preparing AD-35 | NAA50, BBOX1, ADSL | AKR1B1 586/4885SCN9A 3546/4885ACHE 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.