SCHEMBL20751997

SCHEMBL20751997

CNc1c(C)ccc2c1oc1nc(C)ccc12

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 1/20 0.34
KMT2A Q03164 1/20 0.34
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20751962 0.82 ELANE (0.30)
SCHEMBL20751969 0.80 MCL1 (0.42) OPRK1KMT2ANOS1NOS2ALDH1A1
SCHEMBL20751957 0.79 CYP1A2 (0.38) KMT2ANOS1NOS2ALDH1A1
SCHEMBL20752000 0.77 ALDH1A1 (0.37) OPRK1KMT2ANOS1NOS2ALDH1A1
SCHEMBL20751970 0.76 EGFR (0.35) KMT2ANOS1NOS2ALDH1A1
SCHEMBL15705999 0.75 MCL1 (0.40) OPRK1KMT2ANOS1NOS2ALDH1A1
SCHEMBL18052703 0.74 OPRK1 (0.34) OPRK1KMT2ANOS1NOS2ALDH1A1
SCHEMBL19267552 0.74 NOS1 (0.45) OPRK1KMT2ANOS1NOS2ALDH1A1
SCHEMBL19723384 0.74 OPRK1 (0.33) OPRK1KMT2A
SCHEMBL23369161 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3444260-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-02-20 EP disclosed