Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20751969 | 0.82 | MCL1 (0.42) | ALDH1A1KMT2AOPRK1NOS1NOS2 | |
| SCHEMBL20751940 | 0.78 | LMNA (0.46) | ALDH1A1KDM4EGAAHSD17B10LMNA | |
| SCHEMBL15705999 | 0.77 | MCL1 (0.40) | ALDH1A1KMT2AOPRK1NOS1NOS2 | |
| SCHEMBL20751997 | 0.77 | OPRK1 (0.34) | ALDH1A1KMT2AOPRK1NOS1NOS2 | |
| SCHEMBL18052703 | 0.77 | OPRK1 (0.34) | ALDH1A1KMT2AOPRK1NOS1NOS2 | |
| SCHEMBL19267552 | 0.77 | NOS1 (0.45) | ALDH1A1KDM4EGAAKMT2AOPRK1 | |
| SCHEMBL20752034 | 0.76 | GAA (0.36) | GAAKMT2ANOS1NOS2 | |
| SCHEMBL16716130 | 0.75 | NPC1 (0.40) | ALDH1A1KDM4EGAAHSD17B10LMNA | |
| SCHEMBL24729628 | 0.74 | KMT2A (0.39) | ALDH1A1KDM4EGAAHSD17B10LMNA | |
| SCHEMBL20731020 | 0.74 | KMT2A (0.39) | ALDH1A1KDM4EGAAHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3444260-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Universal Display Corporation (US) | 2019-02-20 | — | — | EP | disclosed |