Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.44 |
| ▸ | POLG | P54098 | 2/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 6/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.32 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.32 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19101783 | 0.81 | POLRMT (0.48) | POLRMTPOLGP2RY2P2RY1P2RY11 | |
| SCHEMBL20756764 | 0.81 | — | — | |
| SCHEMBL24942352 | 0.78 | POLRMT (0.52) | POLRMTPOLGP2RY2P2RY1P2RY11 | |
| SCHEMBL24942350 | 0.78 | POLRMT (0.64) | POLRMTP2RY2P2RY1P2RY11 | |
| SCHEMBL20960138 | 0.77 | POLRMT (0.65) | POLRMTPOLGP2RY2P2RY1P2RY11 | |
| SCHEMBL16698714 | 0.77 | POLRMT (0.65) | POLRMTPOLGP2RY2P2RY1P2RY11 | |
| SCHEMBL16698713 | 0.77 | POLRMT (0.65) | POLRMTPOLGP2RY2P2RY1P2RY11 | |
| SCHEMBL4765532 | 0.75 | P2RY2 (0.49) | P2RY2P2RY1P2RY11P2RY4 | |
| SCHEMBL20960076 | 0.74 | POLRMT (0.57) | POLRMTPOLGP2RY2P2RY1P2RY11 | |
| SCHEMBL20959990 | 0.71 | POLRMT (0.59) | POLRMTP2RY2P2RY1P2RY11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10377761-B2 | Pyrrolo[1,2-f][1,2,4]triazines useful for treating respiratory syncitial virus infections | GILEAD SCIENCES, INC. (US) | 2019-08-13 | — | — | US | disclosed |
| US-20190055253-A1 | PYRROLO[1,2-f][1,2,4]TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | GILEAD SCIENCES, INC. | 2019-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10377761-B2 | Pyrrolo[1,2-f][1,2,4]triazines useful for treating respiratory syncitial virus infections | SYNJ1, SARS1, SYNJ2 | POLRMT 306/4885POLG 1293/4885P2RY2 2514/4885 |
| US-20190055253-A1 | PYRROLO[1,2-f][1,2,4]TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | SYNJ1, SARS1, SYNJ2 | POLRMT 306/4885POLG 1293/4885P2RY2 2514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.