Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.32 |
| ▸ | MET | P08581 | 3/20 | 0.32 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | RXRB | P28702 | 2/20 | 0.32 |
| ▸ | RXRG | P48443 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20763167 | 0.95 | TSHR (0.35) | TSHRALDH1A1CYP3A4THRBKIF11 | |
| SCHEMBL20762850 | 0.92 | TSHR (0.40) | TSHRALDH1A1CYP3A4THRBKIF11 | |
| SCHEMBL20762680 | 0.84 | TSHR (0.41) | TSHRALDH1A1CYP3A4THRBKIF11 | |
| SCHEMBL20763225 | 0.84 | THRB (0.39) | TSHRALDH1A1CYP3A4THRBAKR1B10 | |
| SCHEMBL20763399 | 0.83 | TSHR (0.40) | TSHRALDH1A1CYP3A4THRBKIF11 | |
| SCHEMBL20762716 | 0.82 | FFAR4 (0.43) | CYP3A4THRBS1PR1 | |
| SCHEMBL20763163 | 0.81 | RXRA (0.38) | TSHRALDH1A1THRBKIF11AKR1B10 | |
| SCHEMBL20762854 | 0.81 | FFAR4 (0.43) | CYP3A4THRBS1PR1 | |
| SCHEMBL19730203 | 0.81 | TSHR (0.41) | TSHRALDH1A1CYP3A4THRBAKR1B10 | |
| SCHEMBL19738284 | 0.79 | MET (0.41) | TSHRALDH1A1CYP3A4THRBAKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190056676-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND ELECTROPHOTOGRAPHIC APPARATUS AND PROCESS CARTRIDGE EACH INCLUDING THE ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | CANON KABUSHIKI KAISHA (JP) | 2019-02-21 | — | — | US | disclosed |