Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 4/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 5/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20762850 | 0.91 | TSHR (0.40) | THRBTSHRHPGDMETAKR1B10 | |
| SCHEMBL20762680 | 0.85 | TSHR (0.41) | THRBTSHRHPGDMETAKR1B10 | |
| SCHEMBL20763167 | 0.85 | TSHR (0.35) | THRBTSHRHPGDMETAKR1B10 | |
| SCHEMBL20763399 | 0.84 | TSHR (0.40) | THRBTSHRHPGDMETAKR1B10 | |
| SCHEMBL20762866 | 0.84 | TSHR (0.34) | THRBTSHRHPGDMETAKR1B10 | |
| SCHEMBL20762716 | 0.81 | FFAR4 (0.43) | THRBCYP3A4MEN1KMT2A | |
| SCHEMBL20762854 | 0.80 | FFAR4 (0.43) | THRBCYP3A4MEN1KMT2A | |
| SCHEMBL20762909 | 0.80 | RXRA (0.39) | THRBTSHRHPGDMETAKR1B10 | |
| SCHEMBL20762852 | 0.78 | THRB (0.38) | THRBTSHRHPGDMETAKR1B10 | |
| SCHEMBL20762835 | 0.77 | PSEN1 (0.43) | THRBTSHRHPGDAKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190056676-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND ELECTROPHOTOGRAPHIC APPARATUS AND PROCESS CARTRIDGE EACH INCLUDING THE ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | CANON KABUSHIKI KAISHA (JP) | 2019-02-21 | — | — | US | disclosed |