Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 5/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20762850 | 0.84 | TSHR (0.40) | THRBALDH1A1TSHRCYP3A4MET | |
| SCHEMBL20762680 | 0.82 | TSHR (0.41) | THRBALDH1A1TSHRCYP3A4MET | |
| SCHEMBL20763399 | 0.81 | TSHR (0.40) | THRBALDH1A1TSHRCYP3A4MET | |
| SCHEMBL19738184 | 0.81 | MET (0.40) | THRBALDH1A1TSHRCYP3A4MET | |
| SCHEMBL20762835 | 0.79 | PSEN1 (0.43) | THRBALDH1A1TSHRCYP3A4AKR1B10 | |
| SCHEMBL20763167 | 0.78 | TSHR (0.35) | THRBALDH1A1TSHRCYP3A4MET | |
| SCHEMBL20763225 | 0.78 | THRB (0.39) | THRBALDH1A1TSHRCYP3A4MET | |
| SCHEMBL20762847 | 0.78 | THRB (0.40) | THRBALDH1A1TSHRCYP3A4AKR1B10 | |
| SCHEMBL20762866 | 0.78 | TSHR (0.34) | THRBALDH1A1TSHRCYP3A4MET | |
| SCHEMBL20762909 | 0.77 | RXRA (0.39) | THRBALDH1A1TSHRCYP3A4MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190056676-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND ELECTROPHOTOGRAPHIC APPARATUS AND PROCESS CARTRIDGE EACH INCLUDING THE ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | CANON KABUSHIKI KAISHA (JP) | 2019-02-21 | — | — | US | disclosed |