SCHEMBL20764495

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20764434	0.89	CYP3A4 (0.43)	TSHRGAAEP300HIF1AALDH1A1
	SCHEMBL20764437	0.87	MYC (0.41)	TSHRGAAEP300HIF1AALDH1A1
	SCHEMBL15956458	0.86	TSHR (0.40)	TSHRGAAALDH1A1POLBRAB9A
	SCHEMBL20764500	0.85	ALDH1A1 (0.34)	GAAEP300HIF1AALDH1A1POLB
	SCHEMBL17795680	0.85	ALDH1A1 (0.46)	TSHRGAAEP300HIF1AALDH1A1
	SCHEMBL28371567	0.83	CYP3A4 (0.38)	TSHRGAAALDH1A1POLBRAB9A
	SCHEMBL17368443	0.83	TSHR (0.48)	TSHRGAAALDH1A1KDM4ETDP1
	SCHEMBL16392499	0.82	AKR1C3 (0.45)	EP300HIF1AALDH1A1POLBKDM4E
	SCHEMBL16369625	0.81	CTSV (0.48)	POLBTDP1KMT2AL3MBTL1
	SCHEMBL20764503	0.81	EP300 (0.41)	GAAEP300HIF1AALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.