Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 7/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20765497 | 0.94 | MGLL (0.58) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL20765538 | 0.86 | FGFR1 (0.57) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL20782579 | 0.86 | ALDH1A1 (0.55) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL20765467 | 0.84 | ALDH1A1 (0.52) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL20765634 | 0.83 | ALDH1A1 (0.50) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL20765510 | 0.82 | ALDH1A1 (0.48) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL20765776 | 0.81 | ALDH1A1 (0.54) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL20765593 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL20765495 | 0.81 | MGLL (0.56) | MGLLHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL20765671 | 0.80 | ALDH1A1 (0.51) | KDM4EALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038683-A1 | COMPOUNDS TARGETING TANDEM BRCT DOMAINS OF BRCA1, COMPOSITIONS AND METHODS THEREOF | INSTITUTE FOR STEM CELL BIOLOGY AND REGENERATIVE MEDICINE (IN) | 2019-02-28 | — | — | WO | claimed |