SCHEMBL2076642

SCHEMBL2076642

O=C(Cl)c1cccc2c1-c1ccccc1C2=O

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 6/20 0.68
NFE2L2 Q16236 3/20 0.68
ALDH1A1 P00352 5/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
KMT2A Q03164 3/20 0.57
MEN1 O00255 2/20 0.57
SMN1; SMN2 Q16637 1/20 0.55
POLB P06746 3/20 0.54
TP53 P04637 1/20 0.53
ATM Q13315 1/20 0.51
MAPT P10636 2/20 0.50
LMNA P02545 1/20 0.50
HTT P42858 1/20 0.49
USP2 O75604 1/20 0.47
PKM P14618 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8675450 0.92 ALDH1A1 (0.70) KEAP1NFE2L2ALDH1A1L3MBTL1KMT2A
SCHEMBL6989562 0.92 KEAP1 (0.84) KEAP1NFE2L2ALDH1A1L3MBTL1KMT2A
SCHEMBL2402121 0.86 ALDH1A1 (0.50) KEAP1NFE2L2ALDH1A1L3MBTL1KMT2A
SCHEMBL678363 0.85 ALDH1A1 (0.70) KEAP1NFE2L2ALDH1A1L3MBTL1POLB
SCHEMBL11835545 0.83 TTR (0.49) KEAP1NFE2L2ALDH1A1L3MBTL1KMT2A
SCHEMBL600330 0.82 ALDH1A1 (0.85) KEAP1NFE2L2ALDH1A1L3MBTL1KMT2A
SCHEMBL30808237 0.82 ALDH1A1 (0.85) KEAP1NFE2L2ALDH1A1L3MBTL1KMT2A
SCHEMBL31276140 0.82 ALDH1A1 (0.85) KEAP1NFE2L2ALDH1A1L3MBTL1KMT2A
SCHEMBL4930390 0.81 KEAP1 (1.00) KEAP1NFE2L2ALDH1A1L3MBTL1KMT2A
SCHEMBL2605003 0.81 KEAP1 (0.68) KEAP1NFE2L2ALDH1A1L3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026089-B2 Sulfonyldiphenylene based charge transport compositions SAMSUNG ELECTRONICS CO. LTD. (KR) 2006-04-11 US claimed
US-7009062-B2 Process for the preparation of flavone derivatives MERCK PATENT GMBH (DE) 2006-03-07 US claimed
US-20050123848-A1 Sulfonyldiphenylene based charge transport compositions HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2005-06-09 US claimed
US-20250034164-A1 NOVEL COMPOUND AND COMPOSITION FOR PREVENTING OR TREATING NEUROINFLAMMATORY BRAIN DISEASES COMPRISING SAME AS ACTIVE INGREDIENT KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KR) 2025-01-30 US disclosed
EP-4424688-A1 NOVEL COMPOUND AND COMPOSITION FOR PREVENTING OR TREATING NEUROINFLAMMATORY BRAIN DISEASES COMPRISING SAME AS ACTIVE INGREDIENT Korea Institute of Ocean Science & Technology (KR) 2024-09-04 EP disclosed
WO-2023075016-A1 NOVEL COMPOUND AND COMPOSITION FOR PREVENTING OR TREATING NEUROINFLAMMATORY BRAIN DISEASES COMPRISING SAME AS ACTIVE INGREDIENT 한국해양과학기술원 2023-05-04 WO disclosed
CN-105425555-B Electron transport material, Electrophtography photosensor, handle box and imaging device 富士施乐株式会社 2019-12-03 CN disclosed
CN-105892244-B Electrophtography photosensor, handle box and imaging device 富士施乐株式会社 2019-09-27 CN disclosed
US-9563138-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2017-02-07 US disclosed
US-20160238955-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2016-08-18 US disclosed
US-9335644-B2 Electron transport material, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2016-05-10 US disclosed
WO-1997026300-A1 COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES ELI LILLY AND COMPANY (US) 1997-07-24 WO disclosed
US-5424263-A Product formed by contacting silica with hydrocarbon-soluble magnesium compound, heterocyclic fused ring compound having oxygen substituent, modifying silicon, boron or aluminum halide, titanium compound QUANTUM CHEMICAL CORPORATION (US) 1995-06-13 US disclosed
WO-1994025156-A1 SUPPORTED POLYMERIZATION CATALYST QUANTUM CHEMICAL CORPORATION (US) 1994-11-10 WO disclosed
EP-0610745-A2 Novel aminomethylene derivatives as immunosuppressants Bayer Corporation (US) 1994-08-17 EP disclosed
WO-1991005605-A1 CYCLODEXTRIN LABELS FOR IMMUNOASSAY AND BIOCHEMICAL ANALYSIS KOSAK KENNETH M (US) 1991-05-02 WO disclosed
WO-1991002040-A1 CYCLODEXTRIN LABELS FOR NUCLEIC ACID AND BIOCHEMICAL ANALYSIS KOSAK KENNETH M (US) 1991-02-21 WO disclosed
EP-0147226-B1 VISIBLE LIGHT ABSORBING PEROXY ESTERS LOCTITE CORPORATION (US) 1989-11-23 EP disclosed
US-4604295-A VISIBLE AND UV PHOTOINITIATORS FOR CURING ACRYLIC MONOMERS AND PREPOLYMERS LOCTITE CORPORATION (US) 1986-08-05 US disclosed
EP-0147226-A2 Visible light absorbing peroxy esters LOCTITE CORPORATION (US) 1985-07-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250034164-A1 NOVEL COMPOUND AND COMPOSITION FOR PREVENTING OR TREATING NEUROINFLAMMATORY BRAIN DISEASES COMPRISING SAME AS ACTIVE INGREDIENT FABP7, BDNF, PSEN1 KEAP1 35/4885NFE2L2 81/4885ALDH1A1 2021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.