Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 5/20 | 0.43 |
| ▸ | CTSS | P25774 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435998 | 1.00 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19HTTSRC | |
| SCHEMBL29283758 | 0.92 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19HTTSRC | |
| SCHEMBL6566148 | 0.92 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19HTTSRC | |
| SCHEMBL9615714 | 0.90 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19HTTSRC | |
| SCHEMBL12555958 | 0.88 | REN (0.46) | KLK5CTSKCTSSCA12CA14 | |
| SCHEMBL13755357 | 0.88 | REN (0.46) | KLK5CTSKCTSSCA12CA14 | |
| SCHEMBL29058237 | 0.87 | CYP1A2 (0.62) | CYP1A2CYP2C9CYP2C19HTTSRC | |
| SCHEMBL27811871 | 0.87 | CYP1A2 (0.62) | CYP1A2CYP2C9CYP2C19HTTSRC | |
| SCHEMBL7415988 | 0.87 | KLK5 (0.42) | CYP1A2CYP2C9CYP2C19HTTSRC | |
| SCHEMBL7415991 | 0.87 | KLK5 (0.42) | CYP1A2CYP2C9CYP2C19HTTSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250376461-A1 | INDAZOLE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | UNIV LEUVEN KATH (BE) | 2025-12-11 | — | — | US | disclosed |
| EP-4499624-A2 | INDAZOLE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | Katholieke Universiteit Leuven KU Leuven Research & Development (BE) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023230540-A2 | INDAZOLE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| US-10927104-B2 | Ether compounds and uses thereof | BIOTHERYX, INC. (US) | 2021-02-23 | — | — | US | disclosed |
| CN-111592480-A | Preparation method of cefepime intermediate (R) -1-tert-butoxycarbonyl-3-aminopyrrolidine | 山西千岫制药有限公司 | 2020-08-28 | — | — | CN | disclosed |
| US-20200231582-A1 | ETHER COMPOUNDS AND USES THEREOF | BIOTHERYX, INC. | 2020-07-23 | — | — | US | disclosed |
| EP-3672955-A1 | ETHER COMPOUNDS AND USES THEREOF | Biotheryx Inc. (US) | 2020-07-01 | — | — | EP | disclosed |
| WO-2019040274-A1 | ETHER COMPOUNDS AND USES THEREOF | BIOTHERYX, INC. (US) | 2019-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927104-B2 | Ether compounds and uses thereof | EPCAM, ICAM1, SELE | CYP1A2 3444/4885CYP2C9 4374/4885CYP2C19 4640/4885 |
| US-20250376461-A1 | INDAZOLE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | TRPV3, TRPM2, TRPV1 | CYP1A2 1502/4885CYP2C9 2576/4885CYP2C19 1493/4885 |
| US-20200231582-A1 | ETHER COMPOUNDS AND USES THEREOF | EPCAM, ICAM1, SELE | CYP1A2 3444/4885CYP2C9 4374/4885CYP2C19 4640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.