Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 13/20 | 1.00 |
| ▸ | EGFR | P00533 | 3/20 | 1.00 |
| ▸ | ABL1 | P00519 | 1/20 | 0.63 |
| ▸ | ABL2 | P42684 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | TLR4 | O00206 | 1/20 | 0.55 |
| ▸ | TLR2 | O60603 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | GALR2 | O43603 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.53 |
| ▸ | VCP | P55072 | 1/20 | 0.53 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2077031 | 1.00 | FBP1 (1.00) | FBP1EGFRABL1ABL2ALDH1A1 | |
| SCHEMBL6910815 | 0.89 | FBP1 (0.78) | FBP1EGFRABL1ABL2ALDH1A1 | |
| SCHEMBL6910818 | 0.89 | FBP1 (0.78) | FBP1EGFRABL1ABL2ALDH1A1 | |
| SCHEMBL28838361 | 0.81 | TYR (0.69) | FBP1EGFRABL1ABL2ALDH1A1 | |
| SCHEMBL3667077 | 0.79 | EGFR (0.93) | FBP1EGFRABL1ABL2ALDH1A1 | |
| SCHEMBL3667079 | 0.79 | EGFR (0.93) | FBP1EGFRABL1ABL2ALDH1A1 | |
| SCHEMBL421633 | 0.78 | FBP1 (0.64) | FBP1EGFRABL1ABL2ALDH1A1 | |
| SCHEMBL102630 | 0.78 | FBP1 (1.00) | FBP1EGFRABL1ABL2ALDH1A1 | |
| SCHEMBL1681205 | 0.78 | FBP1 (1.00) | FBP1EGFRALDH1A1LMNAMAPT | |
| SCHEMBL366122 | 0.78 | FBP1 (1.00) | FBP1EGFRABL1ABL2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206680-A | Copolymer containing metal element and environment-friendly detection method thereof | 濮阳职业技术学院 | 2024-06-18 | — | — | CN | claimed |
| US-12540144-B2 | Rapafucin derivative compounds and methods of use thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2026-02-03 | — | — | US | disclosed |
| US-20240239810-A1 | RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2024-07-18 | — | — | US | disclosed |
| CN-118206680-A | Copolymer containing metal element and environment-friendly detection method thereof | 濮阳职业技术学院 | 2024-06-18 | — | — | CN | disclosed |
| CN-118206680-A | Copolymer containing metal element and environment-friendly detection method thereof | 濮阳职业技术学院 | 2024-06-18 | — | — | CN | disclosed |
| US-11945827-B2 | Rapafucin derivative compounds and methods of use thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-04-02 | — | — | US | disclosed |
| EP-3189049-B1 | PHTHALAZINE DERIVATIVES OF FORMULA (I) AS PCAF AND GCN5 INHIBITORS FOR USE IN THE TREATMENT OF CANCER | GENENTECH INC (US) | 2024-03-20 | — | — | EP | disclosed |
| EP-3732162-B1 | NITROALKENE NON STEROIDAL ANTI-INFLAMMATORY DRUGS (NA-NSAIDS) AND METHODS OF TREATING INFLAMMATION RELATED CONDITIONS | INST PASTEUR DE MONTEVIDEO (UY) | 2024-03-06 | — | — | EP | disclosed |
| CN-109666121-B | Hybrid dynamic cross-linked polymer and application thereof | 厦门逍扬运动科技有限公司 | 2023-09-22 | — | — | CN | disclosed |
| US-20230000996-A1 | RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2023-01-05 | — | — | US | disclosed |
| EP-0375723-A1 | SUBSTRATES FOR THE ASSAY OF ENZYMES. | KING S COLLEGE LONDON (GB) | 1990-07-04 | — | — | EP | disclosed |
| EP-0346912-A2 | Sugar ester derivatives, reagents for measurement of hydrolase activity and methods for measurement of hydrolase activity | Toyo Boseki Kabushiki Kaisha (JP) | 1989-12-20 | — | — | EP | disclosed |
| WO-1989002473-A1 | SUBSTRATES FOR THE ASSAY OF ENZYMES | KING'S COLLEGE LONDON (GB) | 1989-03-23 | — | — | WO | disclosed |
| EP-0003432-B1 | SYNTHETIC RESIN/GLASS LAMINATES AND PROCESS FOR PRODUCING THESE LAMINATES | CIN Industrial Investments Limited (GB) | 1982-04-07 | — | — | EP | disclosed |
| US-4318986-A | Enzyme assays | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1982-03-09 | — | — | US | disclosed |
| US-4243719-A | Laminates | ROMAG HOLDINGS LTD. (GB) | 1981-01-06 | — | — | US | disclosed |
| EP-0007372-A1 | Methods and reagents for the assay of enzymes | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1980-02-06 | — | — | EP | disclosed |
| EP-0003432-A1 | Synthetic resin/glass laminates and process for producing these laminates | CIN Industrial Investments Limited (GB) | 1979-08-08 | — | — | EP | disclosed |
| WO-1979000255-A1 | ENZYME ASSAYS | NAT RES DEV (GB) | 1979-05-17 | — | — | WO | disclosed |
| US-3985761-A | ANTIBACTERIAL AND ANTHELMINTIC PROPERTIES | SARABHAI RESEARCH CENTRE (IN) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230000996-A1 | RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF | RICTOR, FKBP14, MTOR | FBP1 310/4885EGFR 1567/4885ABL1 3054/4885 |
| US-11945827-B2 | Rapafucin derivative compounds and methods of use thereof | RICTOR, FKBP14, MTOR | FBP1 310/4885EGFR 1567/4885ABL1 3054/4885 |
| US-12540144-B2 | Rapafucin derivative compounds and methods of use thereof | RICTOR, CHP1, FKBP8 | FBP1 1786/4885EGFR 647/4885ABL1 2824/4885 |
| US-20240239810-A1 | RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF | RICTOR, MTOR, FKBP14 | FBP1 225/4885EGFR 1218/4885ABL1 2580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.