Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15338767 | 0.94 | ALDH1A1 (0.40) | HRH3ALDH1A1MAPTNPSR1POLB | |
| SCHEMBL14943772 | 0.86 | NPSR1 (0.38) | HRH3ALDH1A1MAPTNPSR1POLB | |
| SCHEMBL12330396 | 0.76 | NOTUM (0.39) | ALDH1A1MAPTNPSR1MEN1GAA | |
| SCHEMBL19908532 | 0.76 | HRH3 (0.37) | HRH3ALDH1A1MAPTNPSR1POLB | |
| SCHEMBL23729550 | 0.76 | HRH3 (0.42) | HRH3ALDH1A1MAPTNPSR1POLB | |
| SCHEMBL21923271 | 0.75 | KMT2A (0.47) | ALDH1A1MAPTNPSR1POLBHTT | |
| SCHEMBL9675977 | 0.73 | ALDH1A1 (0.49) | ALDH1A1MAPTPOLBSMN1; SMN2MEN1 | |
| SCHEMBL9677304 | 0.73 | KMT2A (0.36) | HRH3ALDH1A1MAPTNPSR1POLB | |
| SCHEMBL12956157 | 0.73 | ALDH1A1 (0.46) | HRH3ALDH1A1MAPTNPSR1POLB | |
| SCHEMBL14256038 | 0.72 | ALDH1A1 (0.56) | ALDH1A1MAPTNPSR1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019043018-A1 | METHODS FOR TREATING OR PREVENTING CARDIOVASCULAR DISORDERS AND LOWERING RISK OF CARDIOVASCULAR EVENTS | DALCOR PHARMA UK LTD., STOCKPORT ZUG BRANCH (CH) | 2019-03-07 | — | — | WO | disclosed |
| US-20160115139-A1 | PROCESS FOR MAKING BENZOXAZINES | CYTEC INDUSTRIES INC. (US) | 2016-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160115139-A1 | PROCESS FOR MAKING BENZOXAZINES | XDH, AFF1, TYR | HRH3 277/4885ALDH1A1 986/4885MAPT 3574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.