Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | TNKS | O95271 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.41 |
| ▸ | UGT2B17 | O75795 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23729552 | 0.94 | TNKS (0.45) | HRH3TNKSPARP1TNKS2UGT2B17 | |
| SCHEMBL14585663 | 0.88 | TNKS (0.36) | HRH3TNKSPARP1TNKS2UGT2B17 | |
| SCHEMBL20780397 | 0.76 | HRH3 (0.41) | HRH3TNKSPARP1TNKS2GAA | |
| SCHEMBL19908532 | 0.74 | HRH3 (0.37) | HRH3GAAALDH1A1KDM4EALOX15 | |
| SCHEMBL23729376 | 0.72 | ALDH1A1 (0.54) | HRH3GAAALDH1A1KDM4ETSHR | |
| SCHEMBL31261723 | 0.70 | MEN1 (0.47) | HRH3UGT2B17TSHRHTR2AHTR2C | |
| SCHEMBL598081 | 0.70 | MEN1 (0.47) | HRH3UGT2B17TSHRHTR2AHTR2C | |
| SCHEMBL14256038 | 0.69 | ALDH1A1 (0.56) | GAAALDH1A1KDM4ETSHRMAPT | |
| SCHEMBL15338767 | 0.69 | ALDH1A1 (0.40) | HRH3TNKSPARP1TNKS2GAA | |
| SCHEMBL5994114 | 0.68 | NOTUM (0.51) | GAAALDH1A1KDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |