Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17571698 | 0.83 | KMT2A (0.35) | KMT2AALDH1A1HPGDMEN1GAA | |
| Hydrochloric Acid SCHEMBL9678474 | 0.83 | KMT2A (0.35) | KMT2AALDH1A1HPGDMEN1GAA | |
| SCHEMBL15338767 | 0.78 | ALDH1A1 (0.40) | KMT2AALDH1A1HPGDMEN1GAA | |
| SCHEMBL9827964 | 0.75 | ALOX12 (0.40) | KMT2AALDH1A1MEN1HRH3 | |
| SCHEMBL16317052 | 0.75 | NOTUM (0.33) | KMT2AALDH1A1HPGDMEN1GAA | |
| SCHEMBL12330396 | 0.75 | NOTUM (0.39) | KMT2AALDH1A1HPGDMEN1GAA | |
| SCHEMBL20780397 | 0.73 | HRH3 (0.41) | KMT2AALDH1A1HPGDMEN1GAA | |
| SCHEMBL12288815 | 0.72 | MET (0.42) | KMT2AALDH1A1HPGDMEN1GAA | |
| SCHEMBL9675977 | 0.71 | ALDH1A1 (0.49) | KMT2AALDH1A1HPGDMEN1GAA | |
| SCHEMBL1105731 | 0.69 | KMT2A (0.55) | KMT2AALDH1A1HPGDMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174717-B1 | BENZIMIDAZOLES, AND THEIR PRODUCTION FORMULATION AND USE AS GASTRIC ACID SECRETION INHIBITORS | FISONS plc (GB) | 1992-01-22 | — | — | EP | disclosed |
| EP-0174717-A1 | Benzimidazoles, and their production formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1986-03-19 | — | — | EP | disclosed |