Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26414391 | 0.76 | MTNR1A (0.45) | — | |
| SCHEMBL5864334 | 0.74 | — | — | |
| SCHEMBL16454157 | 0.72 | — | — | |
| SCHEMBL13472092 | 0.72 | DRD2 (0.34) | DRD2DRD4DRD3 | |
| SCHEMBL8243730 | 0.72 | — | — | |
| SCHEMBL4582309 | 0.71 | PTPN1 (0.32) | — | |
| SCHEMBL10198085 | 0.71 | NAMPT (0.38) | — | |
| SCHEMBL25086461 | 0.70 | HSD17B10 (0.33) | — | |
| SCHEMBL14530586 | 0.70 | PTPN1 (0.31) | — | |
| SCHEMBL21945926 | 0.70 | GABBR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230157290-A1 | ALKENE-CONTAINING CARBOXYLATE COMPOUND AND USE THEREOF | JIANGSU YANGNONG CHEMICAL CO., LTD (CN) | 2023-05-25 | — | — | US | disclosed |
| EP-3675858-B1 | IMIDAZO[1,5-A]PYRAZINE COMPOUNDS AND COMPOSITIONS FOR IRE1 INHIBITION | OPTIKIRA LLC (US) | 2023-04-26 | — | — | EP | disclosed |
| US-20230037883-A1 | ALKENE-CONTAINING AMIDE COMPOUND AND APPLICATION THEREOF | JIANGSU YANGNONG CHEMICAL CO., LTD (CN) | 2023-02-09 | — | — | US | disclosed |
| WO-2019046711-A2 | COMPOUNDS AND COMPOSITIONS FOR IRE1 INHIBITION | OPTIKIRA LLC (US) | 2019-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230157290-A1 | ALKENE-CONTAINING CARBOXYLATE COMPOUND AND USE THEREOF | DDT, ALK, ACMSD | DRD2 1688/4885DRD4 1962/4885DRD3 2313/4885 |
| US-20230037883-A1 | ALKENE-CONTAINING AMIDE COMPOUND AND APPLICATION THEREOF | DDT, ASPH, ALK | DRD2 1638/4885DRD4 1911/4885DRD3 2194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.