Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | EP300 | Q09472 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20787640 | 0.91 | NPC1 (0.49) | NPC1GAAALDH1A1LMNATP53 | |
| SCHEMBL24379800 | 0.83 | MEN1 (0.54) | NPC1GAAALDH1A1MAPTRAB9A | |
| SCHEMBL21138155 | 0.80 | EP300 (0.48) | ALDH1A1LMNAMAPTHSD17B10KDM4E | |
| SCHEMBL20764481 | 0.80 | MEN1 (0.44) | NPC1FFAR1ALDH1A1LMNATP53 | |
| SCHEMBL20764482 | 0.80 | MEN1 (0.44) | NPC1FFAR1ALDH1A1LMNATP53 | |
| SCHEMBL22076696 | 0.80 | MMP2 (0.38) | NPC1GAATP53EP300KMT2A | |
| SCHEMBL22076698 | 0.80 | MMP2 (0.38) | NPC1GAATP53EP300KMT2A | |
| SCHEMBL26543681 | 0.80 | PLG (0.38) | NPC1ALDH1A1LMNATP53MAPT | |
| SCHEMBL24379797 | 0.80 | EP300 (0.53) | NPC1GAAALDH1A1LMNAMAPT | |
| SCHEMBL20764600 | 0.80 | CACNA1B (0.37) | TP53HTTSMN1; SMN2EP300KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038405-A1 | NOVEL CYSTOBACTAMIDE DERIVATIVES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2019-02-28 | — | — | WO | disclosed |