Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MYC | P01106 | 2/20 | 0.45 |
| ▸ | MAX | P61244 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17775442 | 0.91 | ALDH1A1 (0.47) | EP300NPC1HIF1AALDH1A1HTT | |
| SCHEMBL16392463 | 0.91 | EP300 (0.57) | EP300HIF1ABCL2BCL2L1MCL1 | |
| SCHEMBL24379800 | 0.89 | MEN1 (0.54) | NPC1ALDH1A1HTTMEN1MAPT | |
| SCHEMBL21138155 | 0.86 | EP300 (0.48) | EP300HIF1ABCL2BCL2L1MCL1 | |
| SCHEMBL16369610 | 0.85 | EP300 (0.63) | EP300HIF1ABCL2BCL2L1MCL1 | |
| SCHEMBL17784953 | 0.85 | EP300 (0.56) | EP300HIF1ABCL2BCL2L1MCL1 | |
| SCHEMBL17784957 | 0.83 | EP300 (0.58) | EP300NPC1HIF1ABCL2BCL2L1 | |
| SCHEMBL17775416 | 0.83 | EP300 (0.48) | EP300NPC1HIF1ABCL2BCL2L1 | |
| SCHEMBL20787640 | 0.82 | NPC1 (0.49) | NPC1MCL1ALDH1A1HTTMEN1 | |
| SCHEMBL16371049 | 0.82 | MAPT (0.48) | EP300NPC1HIF1ABCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11319279-B2 | Antimicrobial compound and use thereof | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2022-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11319279-B2 | Antimicrobial compound and use thereof | AAAS, VRK1, CACNA1E | EP300 3001/4885NPC1 1774/4885HIF1A 2517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.