Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20786981 | 0.91 | MITF (0.42) | NPC1RAB9AHTTGAAMAPT | |
| SCHEMBL24379800 | 0.87 | MEN1 (0.54) | NPC1RAB9AHTTGAAMAPT | |
| SCHEMBL24379797 | 0.82 | EP300 (0.53) | NPC1RAB9AHTTGAAMAPT | |
| SCHEMBL17775442 | 0.81 | ALDH1A1 (0.47) | NPC1RAB9AHTTGAAMAPT | |
| SCHEMBL20788693 | 0.79 | NPC1 (0.39) | NPC1RAB9AHTTGAAMAPT | |
| SCHEMBL20787628 | 0.78 | MEN1 (0.41) | NPC1RAB9AHTTGAAMAPT | |
| SCHEMBL20787469 | 0.77 | PLAU (0.40) | GAAKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL22099920 | 0.77 | POLB (0.40) | NPC1RAB9AHTTMAPTSMN1; SMN2 | |
| SCHEMBL16371053 | 0.76 | MAPT (0.41) | NPC1RAB9AHTTGAAMAPT | |
| SCHEMBL30625925 | 0.76 | LMNA (0.47) | NPC1RAB9AHTTGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038405-A1 | NOVEL CYSTOBACTAMIDE DERIVATIVES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2019-02-28 | — | — | WO | disclosed |