SCHEMBL2079616

SCHEMBL2079616

CC(C(=O)OO)C(C)(C)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
POLB P06746 1/20 0.44
KDM4E B2RXH2 2/20 0.42
MAPT P10636 3/20 0.41
ADRB2 P07550 2/20 0.41
ADRB1 P08588 2/20 0.41
ADRB3 P13945 2/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41
HSD11B1 P28845 1/20 0.40
HPGD P15428 1/20 0.40
CES1 P23141 1/20 0.40
GAA P10253 2/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29338018 0.77 HSD17B10 (0.48) ALDH1A1POLBKDM4EMAPTTSHR
SCHEMBL2081799 0.74 ALDH1A1 (0.50) ALDH1A1POLBKDM4EMAPTADRB2
SCHEMBL15940043 0.73 TDP1 (0.46) ALDH1A1POLBKDM4EMAPK1NPC1
SCHEMBL16428356 0.72 ALDH1A1 (0.50) ALDH1A1POLBKDM4ETSHRMAPK1
Hydrochloric Acid SCHEMBL21066868 0.71 ALDH1A1 (0.43) ALDH1A1POLBKDM4EMAPTADRB2
SCHEMBL10937260 0.70 CA1 (0.53) ALDH1A1POLBKDM4EMAPTTSHR
SCHEMBL7607688 0.69 MAPK1 (0.52) ALDH1A1POLBKDM4EMAPTMAPK1
SCHEMBL1023276 0.69 HSD11B1 (0.60) ALDH1A1POLBKDM4EMAPK1HSD11B1
SCHEMBL12208260 0.69 HSD11B1 (0.56) ALDH1A1POLBKDM4EMAPK1HSD11B1
SCHEMBL2079617 0.69 ALDH1A1 (0.47) ALDH1A1POLBKDM4EMAPTADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3253561-B1 PROCESS FOR PRODUCING MODIFIED OLEFIN POLYMER IN AN EXTRUDER BOREALIS AG (AT) 2019-05-08 EP claimed
US-9431172-B2 Biaxially oriented electrical insulating film BOREALIS TECHNOLOGY OY (FI) 2016-08-30 US disclosed
US-8163845-B2 Biaxially oriented electrical insulating film TREOFAN GERMANY GMBH & CO. KG (DE) 2012-04-24 US disclosed
EP-1894716-B1 Biaxially oriented, electrically insulating film TREOFAN GERMANY GMBH & CO KG (DE) 2010-11-10 EP disclosed
EP-1894715-B1 Biaxially oriented, electrically insulating film TREOFAN GERMANY GMBH & CO KG (DE) 2010-07-28 EP disclosed
US-20100047544-A1 BIAXIALLY ORIENTED ELECTRICAL INSULATING FILM TREOFAN GERMANY GMBH & CO. KG (DE) 2010-02-25 US disclosed
US-20100003489-A1 BIAXIALLY ORIENTED ELECTRICAL INSULATING FILM TREOFAN GERMANY GMBH & CO. KG (DE) 2010-01-07 US disclosed
EP-1247837-B1 Modified amino resins for semifinished products and molded bodies having an improved resilience AMI AGROLINZ MELAMINE INT GMBH (AT) 2008-05-14 EP disclosed
WO-2008034694-A1 BIAXIALLY ORIENTED ELECTRICAL INSULATING FILM TREOFAN GERMANY GMBH & CO. KG (DE) 2008-03-27 WO disclosed
WO-2008025796-A1 BIAXIALLY ORIENTED ELECTRICAL INSULATING FILM TREOFAN GERMANY GMBH & CO. KG (DE) 2008-03-06 WO disclosed
EP-0915134-A2 Thermoplastic elastomer with high resistance, elasticity and good paintability and high impact resistant polymer blends prepared therefrom Borealis AG (AT) 1999-05-12 EP disclosed
EP-0891989-A1 Modified polymers containing methylene groups PCD Polymere AG (AT) 1999-01-20 EP disclosed
EP-0884355-A1 Polyolefin foams with fine cells PCD Polymere AG (AT) 1998-12-16 EP disclosed
EP-0884335-A1 Segmented polyolefines PCD Polymere AG (AT) 1998-12-16 EP disclosed
EP-0879844-A1 Polyolefin foams with high resistance against deformation by heat PCD Polymere AG (AT) 1998-11-25 EP disclosed
EP-0879830-A1 Modified polypropylene having improved processability PCD Polymere AG (AT) 1998-11-25 EP disclosed
EP-0878567-A2 Polyolefin fibres and polyolefin yarns and textile materials thereof PCD Polymere AG (AT) 1998-11-18 EP disclosed
EP-0821018-A2 Crosslinkable olefinic polymers and method for their preparation PCD-Polymere Gesellschaft m.b.H. (AT) 1998-01-28 EP disclosed
EP-0792894-A2 Continuous modification of polyolefins in solid phase PCD-Polymere Gesellschaft m.b.H. (AT) 1997-09-03 EP disclosed
EP-0787750-A2 Poly(alkylethylene) structural isomers PCD-Polymere Gesellschaft m.b.H. (AT) 1997-08-06 EP disclosed