Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1538287 | 0.79 | HSD17B10 (0.56) | HSD17B10ACHEALDH1A1KDM4EHSD11B1 | |
| SCHEMBL397351 | 0.79 | HSD17B10 (0.56) | HSD17B10ACHEALDH1A1KDM4EHSD11B1 | |
| SCHEMBL6671840 | 0.79 | HSD17B10 (0.56) | HSD17B10ACHEALDH1A1KDM4EHSD11B1 | |
| SCHEMBL677959 | 0.79 | HSD17B10 (0.56) | HSD17B10ACHEALDH1A1KDM4EHSD11B1 | |
| SCHEMBL28551166 | 0.77 | HSD17B10 (0.54) | HSD17B10ACHEALDH1A1KDM4EHSD11B1 | |
| SCHEMBL2079616 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD11B1CA1CA2 | |
| SCHEMBL28455171 | 0.76 | HSD17B10 (0.48) | HSD17B10ACHEALDH1A1KDM4EHSD11B1 | |
| SCHEMBL19286703 | 0.76 | ALDH1A1 (0.54) | HSD17B10ACHEALDH1A1KDM4EHSD11B1 | |
| SCHEMBL27855209 | 0.75 | HSD17B10 (0.64) | HSD17B10ACHEALDH1A1CA1CA2 | |
| SCHEMBL2320664 | 0.75 | CA1 (0.56) | HSD17B10ACHEALDH1A1KDM4EHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239790-A1 | 7-Morpholino-1,6-Naphthyridin-5-yl Derivatives and Pharmaceutical Compositions Thereof Useful as DNA-PK Inhibitor | LIFEARC (GB) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239790-A1 | 7-Morpholino-1,6-Naphthyridin-5-yl Derivatives and Pharmaceutical Compositions Thereof Useful as DNA-PK Inhibitor | DCK, ERCC2, POLK | HSD17B10 2876/4885ACHE 4815/4885ALDH1A1 2208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.